College Football Predictions & CFB Simulator - MyGameSim.com

College Football Predictions for Week 5


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9/25/2025 NCAA FB Games
TimeMatchupPredictionActualResult
7:30 PM  Army @ East Carolina  
by 2.5
East Carolina
WIN 37.8-14.1
won 92.31% of sims, average margin of 23.6
Prediction
East Carolina wins 28-6
 

 
 
9/26/2025 NCAA FB Games
TimeMatchupPredictionActualResult
7 PM  Florida State (8) @ Virginia  
by 7.5
Florida State
WIN 44.9-27.9
won 85.94% of sims, average margin of 16.9
Prediction
Virginia wins 46-38
 

9 PM  TCU @ Arizona State  
by 2.5
Arizona State
WIN 47.1-13.4
won 96.56% of sims, average margin of 33.8
Prediction
Arizona State wins 27-24
 

 
10:30 PM  Houston @ Oregon State  
by 12.5
Oregon State
WIN 18.9-17.7
won 54.69% of sims, average margin of 1.2
Prediction
Houston wins 27-24
 

 
 
9/27/2025 NCAA FB Games
TimeMatchupPredictionActualResult
12 PM  USC (22) @ Illinois  
by 1.5
USC
WIN 41.1-18.6
won 91.05% of sims, average margin of 22.4
Prediction
Illinois wins 34-32
 

12 PM  Notre Dame (2) @ Arkansas  
by 10.5
Arkansas
WIN 44.4-18.9
won 93.16% of sims, average margin of 25.5
Prediction
Notre Dame wins 56-13
 

12 PM  Georgia Tech (13) @ Wake Forest (14) 
by 17
Georgia Tech
WIN 41.5-21.5
won 87.89% of sims, average margin of 20.0
Prediction
Georgia Tech wins 30-29
 

12 PM  Cincinnati (20) @ Kansas (18) 
by 6
Cincinnati
WIN 29.7-27.0
won 58.95% of sims, average margin of 2.7
Prediction
Cincinnati wins 37-34
 

 
 
12 PM  Duke @ Syracuse  
by 6.5
Duke
WIN 33.1-32.6
won 51.58% of sims, average margin of 0.6
Prediction
Duke wins 38-3
 

12 PM  Louisville (12) @ Pittsburgh (10) 
by 5.5
Louisville
WIN 29.7-20.5
won 70.00% of sims, average margin of 9.2
Prediction
Louisville wins 34-27
 

 
 
12 PM  UCF @ Kansas State  
by 5.5
Kansas State
WIN 20.8-18.9
won 56.05% of sims, average margin of 1.9
Prediction
Kansas State wins 34-20
 

12 PM  South Alabama @ North Texas  
by 10.5
North Texas
WIN 32.6-17.7
won 83.16% of sims, average margin of 14.9
Prediction
North Texas wins 36-22
 

 
 
12 PM  Rutgers @ Minnesota  
by 3.5
Minnesota
WIN 27.3-24.8
won 57.37% of sims, average margin of 2.5
Prediction
Minnesota wins 31-28
 

 
 
12 PM  Bowling Green @ Ohio  
by 10
Ohio
WIN 29.8-21.1
won 70.26% of sims, average margin of 8.7
Prediction
Ohio wins 35-20
 

 
12 PM  Norfolk State @ Wagner  
Norfolk State
WIN 24.9-10.1
won 83.89% of sims, average margin of 14.8
Prediction
Wagner wins 18-13
 

12 PM  New Haven @ Duquesne  
Duquesne
WIN 26.7-17.6
won 72.22% of sims, average margin of 9.1
Prediction
Duquesne wins 44-18
 

12 PM  Delaware State @ Sacred Heart  
Sacred Heart
WIN 21.1-20.4
won 53.61% of sims, average margin of 0.6
Prediction
Sacred Heart wins 35-31
 

 
12 PM  Stetson @ Dayton  
Dayton
WIN 23.2-3.8
won 93.33% of sims, average margin of 19.3
Prediction
Dayton wins 48-14
 

12:45 PM  Utah State @ Vanderbilt (9) 
by 21.5
Vanderbilt
WIN 33.3-24.5
won 70.79% of sims, average margin of 8.7
Prediction
Vanderbilt wins 55-35
 

 
1 PM  Eastern Michigan @ Central Michigan  
by 4.5
Central Michigan
WIN 27.9-17.1
won 76.84% of sims, average margin of 10.8
Prediction
Central Michigan wins 24-13
 

 
 
1 PM  Towson @ Bryant  
Bryant
WIN 19.4-18.7
won 52.22% of sims, average margin of 0.8
Prediction
Towson wins 26-24
 

 
1 PM  UAlbany @ New Hampshire  
New Hampshire
WIN 20.2-13.1
won 69.44% of sims, average margin of 7.1
Prediction
New Hampshire wins 24-6
 

1 PM  Marist @ Butler  
Marist
WIN 19.9-12.1
won 72.78% of sims, average margin of 7.7
Prediction
Butler wins 31-28
 

1 PM  Morehead State @ Presbyterian  
Presbyterian
WIN 31.1-21.5
won 72.50% of sims, average margin of 9.6
Prediction
Presbyterian wins 41-0
 

1 PM  Long Island University @ Stonehill  
Stonehill
WIN 17.7-10.1
won 72.78% of sims, average margin of 7.6
Prediction
Stonehill wins 10-3
 

 
1 PM  Holy Cross @ Fordham  
Fordham
WIN 14.4-13.3
won 55.00% of sims, average margin of 1.0
Prediction
Fordham wins 26-21
 

 
1:30 PM  Georgia Southern @ James Madison  
by 12.5
Georgia Southern
WIN 22.9-20.2
won 56.58% of sims, average margin of 2.6
Prediction
James Madison wins 35-10
 

2 PM  Hampton @ Elon  
Elon
WIN 28.0-11.8
won 86.94% of sims, average margin of 16.1
Prediction
Elon wins 41-20
 

 
2 PM  Utah Tech @ Austin Peay  
Austin Peay
WIN 33.5-11.6
won 93.33% of sims, average margin of 21.9
Prediction
Austin Peay wins 42-10
 

2 PM  Howard @ Richmond  
Richmond
WIN 25.1-8.8
won 89.17% of sims, average margin of 16.3
Prediction
Richmond wins 13-12
 

2 PM  South Dakota @ North Dakota State  
North Dakota State
WIN 39.4-12.6
won 95.56% of sims, average margin of 26.8
Prediction
North Dakota State wins 51-13
 

3 PM  Arkansas State @ UL Monroe  
by 1.5
Arkansas State
WIN 27.8-13.3
won 84.47% of sims, average margin of 14.5
Prediction
UL Monroe wins 28-16
 

3 PM  Idaho State @ Northern Colorado  
Idaho State
WIN 26.6-25.8
won 51.39% of sims, average margin of 0.8
Prediction
Idaho State wins 26-18
 

3 PM  Mercyhurst @ South Dakota State  
South Dakota State
WIN 20.7-16.8
won 58.33% of sims, average margin of 3.9
Prediction
South Dakota State wins 51-7
 

3 PM  Alabama A&M @ Bethune-Cookman  
Alabama A&M
WIN 26.6-23.1
won 56.67% of sims, average margin of 3.5
Prediction
Bethune-Cookman wins 41-34
 

3:30 PM  LSU @ Ole Miss (16) 
by 2.5
Ole Miss
WIN 51.3-7.3
won 100.00% of sims, average margin of 43.9
Prediction
Ole Miss wins 24-19
 

 
3:30 PM  Auburn @ Texas A&M (1) 
by 6.5
Texas A&M
WIN 37.5-16.1
won 91.58% of sims, average margin of 21.4
Prediction
Texas A&M wins 16-10
 

3:30 PM  Indiana (7) @ Iowa  
by 3
Indiana
WIN 44.3-6.4
won 100.00% of sims, average margin of 37.9
Prediction
Indiana wins 20-15
 

 
3:30 PM  Ohio State (4) @ Washington (21) 
by 13.5
Ohio State
WIN 32.5-26.7
won 65.26% of sims, average margin of 5.8
Prediction
Ohio State wins 24-6
 

3:30 PM  Rice @ Navy  
by 14
Navy
WIN 32.8-10.6
won 93.42% of sims, average margin of 22.2
Prediction
Navy wins 21-13
 

3:30 PM  San Diego State @ Northern Illinois  
by 2.5
Northern Illinois
WIN 16.5-10.7
won 67.11% of sims, average margin of 5.9
Prediction
San Diego State wins 6-3
 

3:30 PM  Utah @ West Virginia  
by 12.5
West Virginia
WIN 21.3-15.6
won 65.79% of sims, average margin of 5.7
Prediction
Utah wins 48-14
 

3:30 PM  UCLA @ Northwestern  
by 5.5
Northwestern
WIN 28.4-15.7
won 80.26% of sims, average margin of 12.7
Prediction
Northwestern wins 17-14
 

3:30 PM  Baylor @ Oklahoma State  
by 17.5
Baylor
WIN 37.9-16.8
won 91.58% of sims, average margin of 21.1
Prediction
Baylor wins 45-27
 

 
 
3:30 PM  California @ Boston College  
by 4.5
Boston College
WIN 38.6-13.1
won 95.00% of sims, average margin of 25.5
Prediction
California wins 28-24
 

3:30 PM  Connecticut @ Buffalo  
by 2.5
Connecticut
WIN 33.8-14.8
won 86.84% of sims, average margin of 19.0
Prediction
Connecticut wins 20-17
 

 
3:30 PM  Akron @ Toledo (24) 
by 21
Toledo
WIN 29.5-14.3
won 82.89% of sims, average margin of 15.2
Prediction
Toledo wins 45-3
 

3:30 PM  Merrimack @ Stony Brook  
Stony Brook
WIN 25.1-14.3
won 75.28% of sims, average margin of 10.8
Prediction
Stony Brook wins 35-10
 

3:30 PM  North Carolina A&T @ Maine  
Maine
WIN 29.2-5.6
won 96.67% of sims, average margin of 23.5
Prediction
Maine wins 37-30
 

3:30 PM  William & Mary @ Villanova  
Villanova
WIN 23.0-19.7
won 58.33% of sims, average margin of 3.3
Prediction
Villanova wins 31-24
 

 
3:30 PM  Lindenwood @ Miami (Ohio)  
Miami (Ohio)
WIN 24.6-14.7
won 74.86% of sims, average margin of 9.8
Prediction
Miami (Ohio) wins 38-0
 

3:30 PM  Western Carolina @ Campbell  
Western Carolina
WIN 26.9-24.6
won 60.56% of sims, average margin of 2.3
Prediction
Western Carolina wins 42-35
 

 
3:30 PM  Furman @ Samford  
Furman
WIN 28.9-24.6
won 60.83% of sims, average margin of 4.3
Prediction
Furman wins 31-13
 

4 PM  Tulane @ Tulsa  
by 14.5
Tulane
WIN 37.3-14.9
won 91.05% of sims, average margin of 22.4
Prediction
Tulane wins 31-14
 

 
 
4 PM  New Mexico State @ New Mexico  
by 10
New Mexico
WIN 31.0-11.6
won 91.84% of sims, average margin of 19.4
Prediction
New Mexico wins 38-20
 

 
 
4 PM  St. Thomas (MN) @ San Diego  
St. Thomas (MN)
WIN 29.9-16.5
won 80.00% of sims, average margin of 13.3
Prediction
San Diego wins 30-27
 

4 PM  Eastern Illinois @ Western Illinois  
Eastern Illinois
WIN 27.0-19.1
won 68.89% of sims, average margin of 8.0
Prediction
Eastern Illinois wins 31-23
 

 
4 PM  Eastern Washington @ Montana State  
Montana State
WIN 30.0-15.5
won 83.33% of sims, average margin of 14.5
Prediction
Montana State wins 57-3
 

4:10 PM  Hawaii @ Air Force  
by 5.5
Air Force
WIN 31.3-17.6
won 79.47% of sims, average margin of 13.7
Prediction
Hawaii wins 44-35
 

4:15 PM  Tennessee (23) @ Mississippi State  
by 10
Tennessee
WIN 32.6-29.1
won 59.47% of sims, average margin of 3.5
Prediction
Tennessee wins 41-34
 

 
 
4:30 PM  Tennessee Tech @ Tennessee State  
Tennessee Tech
WIN 43.0-4.8
won 100.00% of sims, average margin of 38.2
Prediction
Tennessee Tech wins 35-8
 

5 PM  Northern Arizona @ Portland State  
Northern Arizona
WIN 27.6-12.4
won 85.56% of sims, average margin of 15.1
Prediction
Northern Arizona wins 31-17
 

 
5 PM  Texas Southern @ Mississippi Valley State  
Texas Southern
WIN 17.9-16.6
won 51.94% of sims, average margin of 1.3
Prediction
Texas Southern wins 23-20
 

 
5:30 PM  Mercer @ East Tennessee State  
Mercer
WIN 32.4-15.1
won 84.17% of sims, average margin of 17.3
Prediction
Mercer wins 38-34
 

6 PM  Liberty @ Old Dominion  
by 8.5
Old Dominion
WIN 50.2-7.9
won 99.47% of sims, average margin of 42.3
Prediction
Old Dominion wins 21-7
 

 
6 PM  Middle Tennessee @ Kennesaw State  
by 7
Kennesaw State
WIN 32.6-15.4
won 84.74% of sims, average margin of 17.3
Prediction
Kennesaw State wins 24-16
 

 
6 PM  Citadel @ Chattanooga  
Chattanooga
WIN 22.5-18.6
won 62.22% of sims, average margin of 3.8
Prediction
Citadel wins 28-10
 

6 PM  Nicholls State @ Eastern Kentucky  
Nicholls State
WIN 20.1-7.9
won 83.33% of sims, average margin of 12.2
Prediction
Eastern Kentucky wins 27-7
 

6 PM  South Carolina State @ Charleston Southern  
South Carolina State
WIN 23.6-11.0
won 80.28% of sims, average margin of 12.5
Prediction
Charleston Southern wins 31-24
 

6 PM  St. Francis (PA) @ Bucknell  
Bucknell
WIN 23.7-17.8
won 66.11% of sims, average margin of 5.8
Prediction
Bucknell wins 30-23
 

 
6:30 PM  Rhode Island @ Western Michigan  
Rhode Island
WIN 26.9-9.1
won 88.51% of sims, average margin of 17.8
Prediction
Western Michigan wins 47-14
 

7 PM  Arizona @ Iowa State  
by 7
Iowa State
WIN 20.6-20.3
won 48.68% of sims, average margin of 0.3
Prediction
Iowa State wins 39-14
 

7 PM  Virginia Tech @ NC State  
by 7.5
NC State
WIN 37.1-18.4
won 88.16% of sims, average margin of 18.7
Prediction
Virginia Tech wins 23-21
 

7 PM  Memphis @ Florida Atlantic  
by 14
Memphis
WIN 35.0-18.1
won 85.26% of sims, average margin of 17.0
Prediction
Memphis wins 55-26
 

 
7 PM  Jacksonville State @ Southern Miss  
by 2.5
Southern Miss
WIN 38.3-14.5
won 91.84% of sims, average margin of 23.8
Prediction
Southern Miss wins 42-25
 

 
 
7 PM  Western Kentucky @ Missouri State  
by 7
Western Kentucky
WIN 34.0-17.5
won 86.84% of sims, average margin of 16.5
Prediction
Western Kentucky wins 27-22
 

7 PM  Abilene Christian @ Incarnate Word  
Incarnate Word
WIN 28.5-17.4
won 76.67% of sims, average margin of 11.1
Prediction
Incarnate Word wins 38-7
 

7 PM  North Carolina Central @ East Texas A&M  
North Carolina Central
WIN 32.4-17.7
won 82.78% of sims, average margin of 14.8
Prediction
North Carolina Central wins 50-42
 

 
7 PM  Grambling State @ Prairie View  
Prairie View
WIN 28.6-18.1
won 75.00% of sims, average margin of 10.5
Prediction
Prairie View wins 28-13
 

 
7 PM  Southeast Missouri State @ UT-Martin  
Southeast Missouri State
WIN 22.7-19.3
won 58.61% of sims, average margin of 3.4
Prediction
UT-Martin wins 34-10
 

7 PM  Arkansas-Pine Bluff @ Alcorn State  
Arkansas-Pine Bluff
WIN 18.9-12.0
won 70.00% of sims, average margin of 6.9
Prediction
Arkansas-Pine Bluff wins 24-20
 

 
7 PM  Jackson State @ Southern University  
Jackson State
WIN 21.8-12.3
won 72.50% of sims, average margin of 9.5
Prediction
Jackson State wins 38-13
 

7 PM  Central Arkansas @ Lamar  
Central Arkansas
WIN 27.3-5.9
won 96.39% of sims, average margin of 21.4
Prediction
Lamar wins 35-32
 

7:30 PM  Alabama @ Georgia  
by 4
Alabama
WIN 47.1-13.5
won 98.42% of sims, average margin of 33.5
Prediction
Alabama wins 24-21
 

 
7:30 PM  Oregon @ Penn State  
by 6.5
Oregon
WIN 24.9-23.3
won 54.21% of sims, average margin of 1.6
Prediction
Oregon wins 30-24
 

 
 
7:30 PM  Washington State @ Colorado State  
by 4
Colorado State
WIN 19.9-17.3
won 58.42% of sims, average margin of 2.6
Prediction
Washington State wins 20-3
 

 
7:30 PM  Massachusetts @ Missouri  
by 42.5
Missouri
WIN 53.0-5.9
won 100.00% of sims, average margin of 47.1
Prediction
Missouri wins 42-6
 

7:30 PM  Appalachian State @ Boise State (25) 
by 17.5
Boise State
WIN 40.9-22.9
won 83.42% of sims, average margin of 18.0
Prediction
Boise State wins 47-14
 

 
7:30 PM  San Jose State @ Stanford  
by 1.5
San Jose State
WIN 27.4-18.2
won 73.68% of sims, average margin of 9.1
Prediction
Stanford wins 30-29
 

 
7:45 PM  Kentucky @ South Carolina  
by 6
Kentucky
WIN 28.4-16.8
won 79.74% of sims, average margin of 11.6
Prediction
South Carolina wins 35-13
 

8 PM  Marshall @ Louisiana  
by 3.5
Marshall
WIN 28.6-13.3
won 83.68% of sims, average margin of 15.3
Prediction
Louisiana wins 54-51
 

 
8 PM  McNeese @ SFA  
SFA
WIN 24.1-17.4
won 68.06% of sims, average margin of 6.7
Prediction
SFA wins 34-17
 

8:30 PM  West Georgia @ Southern Utah  
West Georgia
WIN 25.3-22.5
won 57.22% of sims, average margin of 2.8
Prediction
West Georgia wins 27-24
 

 
9 PM  Louisiana Tech @ UTEP  
by 4
Louisiana Tech
WIN 20.7-19.4
won 52.11% of sims, average margin of 1.3
Prediction
Louisiana Tech wins 30-11
 

9 PM  Cal Poly @ Sacramento State  
Sacramento State
WIN 41.3-23.1
won 85.28% of sims, average margin of 18.1
Prediction
Cal Poly wins 32-24
 

10 PM  Weber State @ UC Davis  
UC Davis
WIN 33.7-16.2
won 83.61% of sims, average margin of 17.5
Prediction
UC Davis wins 34-12
 

 
10:15 PM  BYU (19) @ Colorado  
by 4
Colorado
WIN 32.6-15.2
won 87.63% of sims, average margin of 17.4
Prediction
BYU wins 24-21
 

 
10:15 PM  Idaho @ Montana  
Montana
WIN 45.2-16.1
won 96.67% of sims, average margin of 29.0
Prediction
Montana wins 41-30
 

Legend/Totals

 TotalTop 25
Correct Picks 70 (71.4%)11 (73.3%)
Incorrect Picks 28 (28.6%)4 (26.7%)
Final Margin within 5 Pts 30 (30.6%)3 (20.0%)
Beat the Spread 27 (52.9%)8 (53.3%)

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