College Football Predictions & CFB Simulator - MyGameSim.com

College Football Predictions for Week 5


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9/25/2025 NCAA FB Games
TimeMatchupPredictionActualResult
7:30 PM  Army @ East Carolina  
O/U 52.50
East Carolina
WIN 37.8-14.1
won 92.31% of sims, total points 51.9
Prediction
East Carolina wins 28-6
 

 
 
9/26/2025 NCAA FB Games
TimeMatchupPredictionActualResult
7 PM  Florida State (8) @ Virginia  
O/U 51.50
Florida State
WIN 44.9-27.9
won 85.94% of sims, total points 72.8
Prediction
Virginia wins 46-38
 

 
9 PM  TCU @ Arizona State  
Arizona State
WIN 47.1-13.4
won 96.56% of sims, total points 60.5
Prediction
Arizona State wins 27-24
 

10:30 PM  Houston @ Oregon State  
Oregon State
WIN 18.9-17.7
won 54.69% of sims, total points 36.6
Prediction
Houston wins 27-24
 

 
9/27/2025 NCAA FB Games
TimeMatchupPredictionActualResult
12 PM  USC (22) @ Illinois  
O/U 56.50
USC
WIN 41.1-18.6
won 91.05% of sims, total points 59.7
Prediction
Illinois wins 34-32
 

 
12 PM  Notre Dame (2) @ Arkansas  
O/U 58.50
Arkansas
WIN 44.4-18.9
won 93.16% of sims, total points 63.3
Prediction
Notre Dame wins 56-13
 

 
12 PM  Georgia Tech (13) @ Wake Forest (14) 
O/U 54.00
Georgia Tech
WIN 41.5-21.5
won 87.89% of sims, total points 63.1
Prediction
Georgia Tech wins 30-29
 

 
12 PM  Cincinnati (20) @ Kansas (18) 
O/U 55.50
Cincinnati
WIN 29.7-27.0
won 58.95% of sims, total points 56.7
Prediction
Cincinnati wins 37-34
 

 
 
12 PM  Duke @ Syracuse  
O/U 59.00
Duke
WIN 33.1-32.6
won 51.58% of sims, total points 65.7
Prediction
Duke wins 38-3
 

12 PM  Louisville (12) @ Pittsburgh (10) 
O/U 56.50
Louisville
WIN 29.7-20.5
won 70.00% of sims, total points 50.1
Prediction
Louisville wins 34-27
 

 
12 PM  UCF @ Kansas State  
Kansas State
WIN 20.8-18.9
won 56.05% of sims, total points 39.8
Prediction
Kansas State wins 34-20
 

12 PM  South Alabama @ North Texas  
O/U 63.00
North Texas
WIN 32.6-17.7
won 83.16% of sims, total points 50.3
Prediction
North Texas wins 36-22
 

 
 
12 PM  Rutgers @ Minnesota  
Minnesota
WIN 27.3-24.8
won 57.37% of sims, total points 52.2
Prediction
Minnesota wins 31-28
 

 
12 PM  Bowling Green @ Ohio  
O/U 51.00
Ohio
WIN 29.8-21.1
won 70.26% of sims, total points 50.9
Prediction
Ohio wins 35-20
 

 
12:45 PM  Utah State @ Vanderbilt (9) 
O/U 59.50
Vanderbilt
WIN 33.3-24.5
won 70.79% of sims, total points 57.8
Prediction
Vanderbilt wins 55-35
 

1 PM  Eastern Michigan @ Central Michigan  
O/U 54.00
Central Michigan
WIN 27.9-17.1
won 76.84% of sims, total points 45.0
Prediction
Central Michigan wins 24-13
 

 
 
1:30 PM  Georgia Southern @ James Madison  
O/U 54.00
Georgia Southern
WIN 22.9-20.2
won 56.58% of sims, total points 43.1
Prediction
James Madison wins 35-10
 

 
3 PM  Arkansas State @ UL Monroe  
O/U 56.50
Arkansas State
WIN 27.8-13.3
won 84.47% of sims, total points 41.1
Prediction
UL Monroe wins 28-16
 

 
3:30 PM  LSU @ Ole Miss (16) 
O/U 56.50
Ole Miss
WIN 51.3-7.3
won 100.00% of sims, total points 58.6
Prediction
Ole Miss wins 24-19
 

3:30 PM  Auburn @ Texas A&M (1) 
O/U 46.50
Texas A&M
WIN 37.5-16.1
won 91.58% of sims, total points 53.6
Prediction
Texas A&M wins 16-10
 

3:30 PM  Indiana (7) @ Iowa  
O/U 48.50
Indiana
WIN 44.3-6.4
won 100.00% of sims, total points 50.7
Prediction
Indiana wins 20-15
 

3:30 PM  Ohio State (4) @ Washington (21) 
O/U 48.50
Ohio State
WIN 32.5-26.7
won 65.26% of sims, total points 59.1
Prediction
Ohio State wins 24-6
 

3:30 PM  Rice @ Navy  
O/U 45.50
Navy
WIN 32.8-10.6
won 93.42% of sims, total points 43.4
Prediction
Navy wins 21-13
 

 
3:30 PM  San Diego State @ Northern Illinois  
O/U 43.00
Northern Illinois
WIN 16.5-10.7
won 67.11% of sims, total points 27.2
Prediction
San Diego State wins 6-3
 

 
3:30 PM  Utah @ West Virginia  
O/U 50.50
West Virginia
WIN 21.3-15.6
won 65.79% of sims, total points 36.9
Prediction
Utah wins 48-14
 

3:30 PM  UCLA @ Northwestern  
O/U 46.00
Northwestern
WIN 28.4-15.7
won 80.26% of sims, total points 44.1
Prediction
Northwestern wins 17-14
 

 
3:30 PM  Baylor @ Oklahoma State  
O/U 59.50
Baylor
WIN 37.9-16.8
won 91.58% of sims, total points 54.7
Prediction
Baylor wins 45-27
 

 
3:30 PM  California @ Boston College  
O/U 52.00
Boston College
WIN 38.6-13.1
won 95.00% of sims, total points 51.7
Prediction
California wins 28-24
 

3:30 PM  Connecticut @ Buffalo  
O/U 51.50
Connecticut
WIN 33.8-14.8
won 86.84% of sims, total points 48.6
Prediction
Connecticut wins 20-17
 

 
3:30 PM  Akron @ Toledo (24) 
O/U 48.50
Toledo
WIN 29.5-14.3
won 82.89% of sims, total points 43.8
Prediction
Toledo wins 45-3
 

 
3:30 PM  Lindenwood @ Miami (Ohio)  
Miami (Ohio)
WIN 24.6-14.7
won 74.86% of sims, total points 39.3
Prediction
Miami (Ohio) wins 38-0
 

4 PM  Tulane @ Tulsa  
O/U 55.00
Tulane
WIN 37.3-14.9
won 91.05% of sims, total points 52.2
Prediction
Tulane wins 31-14
 

 
 
4 PM  New Mexico State @ New Mexico  
O/U 54.50
New Mexico
WIN 31.0-11.6
won 91.84% of sims, total points 42.6
Prediction
New Mexico wins 38-20
 

 
4:10 PM  Hawaii @ Air Force  
O/U 54.00
Air Force
WIN 31.3-17.6
won 79.47% of sims, total points 49.0
Prediction
Hawaii wins 44-35
 

4:15 PM  Tennessee (23) @ Mississippi State  
O/U 62.50
Tennessee
WIN 32.6-29.1
won 59.47% of sims, total points 61.6
Prediction
Tennessee wins 41-34
 

 
6 PM  Liberty @ Old Dominion  
O/U 51.00
Old Dominion
WIN 50.2-7.9
won 99.47% of sims, total points 58.1
Prediction
Old Dominion wins 21-7
 

6 PM  Middle Tennessee @ Kennesaw State  
O/U 51.00
Kennesaw State
WIN 32.6-15.4
won 84.74% of sims, total points 48.0
Prediction
Kennesaw State wins 24-16
 

 
6:30 PM  Rhode Island @ Western Michigan  
Rhode Island
WIN 26.9-9.1
won 88.51% of sims, total points 36.0
Prediction
Western Michigan wins 47-14
 

7 PM  Arizona @ Iowa State  
O/U 49.50
Iowa State
WIN 20.6-20.3
won 48.68% of sims, total points 41.0
Prediction
Iowa State wins 39-14
 

7 PM  Virginia Tech @ NC State  
O/U 57.00
NC State
WIN 37.1-18.4
won 88.16% of sims, total points 55.4
Prediction
Virginia Tech wins 23-21
 

 
7 PM  Memphis @ Florida Atlantic  
O/U 61.50
Memphis
WIN 35.0-18.1
won 85.26% of sims, total points 53.1
Prediction
Memphis wins 55-26
 

7 PM  Jacksonville State @ Southern Miss  
O/U 57.00
Southern Miss
WIN 38.3-14.5
won 91.84% of sims, total points 52.8
Prediction
Southern Miss wins 42-25
 

 
7 PM  Western Kentucky @ Missouri State  
O/U 59.50
Western Kentucky
WIN 34.0-17.5
won 86.84% of sims, total points 51.5
Prediction
Western Kentucky wins 27-22
 

 
7:30 PM  Alabama @ Georgia  
O/U 52.50
Alabama
WIN 47.1-13.5
won 98.42% of sims, total points 60.6
Prediction
Alabama wins 24-21
 

7:30 PM  Oregon @ Penn State  
O/U 52.50
Oregon
WIN 24.9-23.3
won 54.21% of sims, total points 48.2
Prediction
Oregon wins 30-24
 

 
7:30 PM  Washington State @ Colorado State  
O/U 50.50
Colorado State
WIN 19.9-17.3
won 58.42% of sims, total points 37.2
Prediction
Washington State wins 20-3
 

 
7:30 PM  Massachusetts @ Missouri  
O/U 55.00
Missouri
WIN 53.0-5.9
won 100.00% of sims, total points 58.9
Prediction
Missouri wins 42-6
 

7:30 PM  Appalachian State @ Boise State (25) 
O/U 58.50
Boise State
WIN 40.9-22.9
won 83.42% of sims, total points 63.8
Prediction
Boise State wins 47-14
 

 
7:30 PM  San Jose State @ Stanford  
O/U 49.50
San Jose State
WIN 27.4-18.2
won 73.68% of sims, total points 45.6
Prediction
Stanford wins 30-29
 

7:45 PM  Kentucky @ South Carolina  
O/U 47.00
Kentucky
WIN 28.4-16.8
won 79.74% of sims, total points 45.2
Prediction
South Carolina wins 35-13
 

8 PM  Marshall @ Louisiana  
O/U 46.50
Marshall
WIN 28.6-13.3
won 83.68% of sims, total points 42.0
Prediction
Louisiana wins 54-51
 

9 PM  Louisiana Tech @ UTEP  
O/U 48.50
Louisiana Tech
WIN 20.7-19.4
won 52.11% of sims, total points 40.2
Prediction
Louisiana Tech wins 30-11
 

 
10:15 PM  BYU (19) @ Colorado  
O/U 47.50
Colorado
WIN 32.6-15.2
won 87.63% of sims, total points 47.8
Prediction
BYU wins 24-21
 

Legend/Totals

 TotalTop 25
Correct Picks 36 (67.9%)11 (73.3%)
Incorrect Picks 17 (32.1%)4 (26.7%)
Final Margin within 5 Pts 14 (26.4%)3 (20.0%)
Beat the Spread 22 (46.8%)0 (0.0%)

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