College Football Predictions & CFB Simulator - MyGameSim.com

College Football Predictions for Week 6


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10/2/2025 NCAA FB Games
TimeMatchupPredictionActualResult
9 PM  Sam Houston @ New Mexico State  
O/U 52.50
New Mexico State
WIN 22.6-10.3
won 79.21% of sims, total points 32.9
Prediction
New Mexico State wins 37-10
 

 
10/3/2025 NCAA FB Games
TimeMatchupPredictionActualResult
7 PM  Western Kentucky @ Delaware  
O/U 61.50
Western Kentucky
WIN 31.3-21.2
won 71.56% of sims, total points 52.6
Prediction
Western Kentucky wins 27-24
 

 
7 PM  Charlotte @ USF  
USF
WIN 49.8-7.2
won 99.69% of sims, total points 56.9
Prediction
USF wins 54-26
 

7 PM  Rhode Island @ Brown  
Rhode Island
WIN 24.6-13.0
won 77.67% of sims, total points 37.7
Prediction
Brown wins 28-20
 

10 PM  New Mexico @ San Jose State  
O/U 55.50
San Jose State
WIN 27.6-21.8
won 63.44% of sims, total points 49.5
Prediction
San Jose State wins 35-28
 

 
10:30 PM  West Virginia @ BYU (19) 
O/U 49.50
BYU
WIN 32.5-12.3
won 90.94% of sims, total points 44.8
Prediction
BYU wins 38-24
 

 
10:30 PM  Colorado State @ San Diego State  
O/U 39.00
Colorado State
WIN 12.9-12.2
won 52.19% of sims, total points 25.1
Prediction
San Diego State wins 45-24
 

10/4/2025 NCAA FB Games
TimeMatchupPredictionActualResult
12 PM  Wisconsin @ Michigan (5) 
O/U 41.50
Michigan
WIN 43.9-6.4
won 99.47% of sims, total points 50.3
Prediction
Michigan wins 24-10
 

12 PM  Iowa State @ Cincinnati (20) 
O/U 51.50
Cincinnati
WIN 42.1-16.8
won 96.05% of sims, total points 58.9
Prediction
Cincinnati wins 38-30
 

 
12 PM  Illinois @ Purdue  
O/U 54.50
Illinois
WIN 30.1-21.1
won 71.05% of sims, total points 51.2
Prediction
Illinois wins 43-27
 

12 PM  Kentucky @ Georgia  
O/U 50.50
Georgia
WIN 27.4-24.8
won 57.11% of sims, total points 52.2
Prediction
Georgia wins 35-14
 

12 PM  Air Force @ Navy  
Navy
WIN 33.4-32.9
won 49.21% of sims, total points 66.3
Prediction
Navy wins 34-31
 

 
12 PM  Kansas State @ Baylor  
Kansas State
WIN 26.5-20.3
won 67.89% of sims, total points 46.8
Prediction
Baylor wins 35-34
 

12 PM  Clemson @ UNC  
O/U 48.50
Clemson
WIN 33.0-10.1
won 93.16% of sims, total points 43.1
Prediction
Clemson wins 38-10
 

 
 
12 PM  Army @ UAB  
O/U 58.50
UAB
WIN 32.7-20.0
won 76.84% of sims, total points 52.8
Prediction
Army wins 31-13
 

 
12 PM  Ohio @ Ball State  
O/U 51.50
Ohio
WIN 32.2-15.8
won 86.58% of sims, total points 47.9
Prediction
Ball State wins 20-14
 

 
12 PM  Boston College @ Pittsburgh (10) 
O/U 54.50
Pittsburgh
WIN 31.2-24.0
won 66.32% of sims, total points 55.3
Prediction
Pittsburgh wins 48-7
 

 
12 PM  San Diego @ Marist  
San Diego
WIN 17.4-12.3
won 66.39% of sims, total points 29.7
Prediction
Marist wins 19-7
 

12 PM  Sacred Heart @ CCSU  
CCSU
WIN 24.0-20.8
won 61.39% of sims, total points 44.7
Prediction
CCSU wins 42-35
 

 
12 PM  Yale @ Lehigh  
Lehigh
WIN 37.1-11.3
won 96.39% of sims, total points 48.4
Prediction
Lehigh wins 24-13
 

12 PM  Stonehill @ Duquesne  
Duquesne
WIN 22.5-13.4
won 73.89% of sims, total points 35.9
Prediction
Duquesne wins 34-7
 

12 PM  Rhode Island @ Brown  
Rhode Island
WIN 24.4-12.8
won 78.89% of sims, total points 37.2
Prediction | Simulate
 
 
12 PM  Richmond @ Bucknell  
Richmond
WIN 22.8-17.5
won 64.17% of sims, total points 40.2
Prediction
Bucknell wins 33-28
 

12:30 PM  Fordham @ Lafayette  
Lafayette
WIN 36.0-9.7
won 96.67% of sims, total points 45.8
Prediction
Lafayette wins 24-10
 

1 PM  Wake Forest (14) @ Virginia Tech  
O/U 50.50
Virginia Tech
WIN 28.5-15.2
won 82.63% of sims, total points 43.8
Prediction
Wake Forest wins 30-23
 

1 PM  TX-San Antonio @ Temple  
O/U 58.50
TX-San Antonio
WIN 30.3-19.9
won 73.16% of sims, total points 50.2
Prediction
Temple wins 27-21
 

 
1 PM  Dartmouth @ Pennsylvania  
Dartmouth
WIN 26.9-25.9
won 50.83% of sims, total points 52.8
Prediction
Pennsylvania wins 33-24
 

1 PM  Long Island University @ Mercyhurst  
Mercyhurst
WIN 28.7-9.0
won 91.11% of sims, total points 37.7
Prediction
Mercyhurst wins 22-13
 

1 PM  Delaware State @ Monmouth  
Monmouth
WIN 44.8-20.8
won 91.94% of sims, total points 65.6
Prediction
Monmouth wins 42-38
 

1 PM  Villanova @ New Hampshire  
New Hampshire
WIN 22.5-19.5
won 56.94% of sims, total points 42.0
Prediction
Villanova wins 37-7
 

1 PM  Morgan State @ Georgetown  
Georgetown
WIN 31.2-13.9
won 84.17% of sims, total points 45.1
Prediction
Morgan State wins 24-21
 

1 PM  Davidson @ Stetson  
Stetson
WIN 19.2-7.2
won 80.56% of sims, total points 26.4
Prediction
Stetson wins 34-24
 

 
1 PM  Dayton @ Morehead State  
Dayton
WIN 24.4-14.0
won 77.78% of sims, total points 38.4
Prediction
 
 

1 PM  Valparaiso @ Drake  
Drake
WIN 21.3-15.1
won 67.50% of sims, total points 36.4
Prediction
Drake wins 34-0
 

1 PM  Robert Morris @ Merrimack  
Merrimack
WIN 25.1-7.8
won 91.94% of sims, total points 32.9
Prediction
Merrimack wins 17-7
 

1 PM  Western Illinois @ Tennessee Tech  
Tennessee Tech
WIN 41.8-8.3
won 98.01% of sims, total points 50.2
Prediction
Tennessee Tech wins 66-20
 

1:30 PM  Western Carolina @ Wofford  
Western Carolina
WIN 26.2-10.7
won 89.33% of sims, total points 36.9
Prediction
Western Carolina wins 23-21
 

1:30 PM  Chattanooga @ VMI  
Chattanooga
WIN 26.1-19.2
won 65.33% of sims, total points 45.3
Prediction
Chattanooga wins 21-14
 

 
1:30 PM  Charleston Southern @ Gardner-Webb  
Gardner-Webb
WIN 34.9-9.8
won 93.00% of sims, total points 44.7
Prediction
Gardner-Webb wins 24-20
 

2 PM  Campbell @ NC State  
NC State
WIN 34.3-13.8
won 89.85% of sims, total points 48.1
Prediction
NC State wins 56-10
 

2 PM  East Tennessee State @ Furman  
Furman
WIN 29.8-15.2
won 82.67% of sims, total points 45.1
Prediction
Furman wins 25-22
 

2 PM  Butler @ St. Thomas (MN)  
St. Thomas (MN)
WIN 34.5-18.1
won 83.67% of sims, total points 52.6
Prediction
 
 

2 PM  Colgate @ Cornell  
Colgate
WIN 25.9-15.8
won 72.67% of sims, total points 41.6
Prediction
Colgate wins 34-21
 

 
2 PM  Harvard @ Holy Cross  
Harvard
WIN 39.2-5.4
won 99.67% of sims, total points 44.6
Prediction
Harvard wins 59-10
 

2 PM  Maine @ Bryant  
Bryant
WIN 19.6-15.3
won 61.67% of sims, total points 34.9
Prediction
Maine wins 34-7
 

2 PM  UT-Martin @ Lindenwood  
UT-Martin
WIN 20.5-15.6
won 66.33% of sims, total points 36.1
Prediction
Lindenwood wins 30-7
 

2:30 PM  Western Michigan @ Massachusetts  
O/U 47.50
Western Michigan
WIN 18.6-13.7
won 65.53% of sims, total points 32.3
Prediction
Western Michigan wins 21-3
 

 
3 PM  Oklahoma State @ Arizona  
O/U 55.50
Arizona
WIN 37.8-9.9
won 97.11% of sims, total points 47.7
Prediction
Arizona wins 41-13
 

 
 
3 PM  Murray State @ South Dakota  
South Dakota
WIN 33.8-7.2
won 96.67% of sims, total points 41.0
Prediction
South Dakota wins 49-17
 

 
3 PM  Florida A&M @ Mississippi Valley State  
Florida A&M
WIN 24.0-13.8
won 78.67% of sims, total points 37.9
Prediction | Simulate
 
 
3 PM  Bethune-Cookman @ Alabama State  
Alabama State
WIN 31.0-21.2
won 74.00% of sims, total points 52.2
Prediction
Alabama State wins 52-35
 

3 PM  North Alabama @ Abilene Christian  
Abilene Christian
WIN 22.9-18.6
won 63.67% of sims, total points 41.6
Prediction
Abilene Christian wins 45-10
 

3 PM  Tennessee State @ Eastern Illinois  
Eastern Illinois
WIN 27.9-7.3
won 95.67% of sims, total points 35.2
Prediction
Eastern Illinois wins 31-7
 

 
3:30 PM  Vanderbilt (9) @ Alabama  
O/U 51.50
Alabama
WIN 30.1-27.5
won 59.06% of sims, total points 57.6
Prediction
Alabama wins 30-14
 

3:30 PM  Virginia @ Louisville (12) 
O/U 61.50
Louisville
WIN 34.1-28.9
won 61.84% of sims, total points 63.0
Prediction
Virginia wins 30-27
 

3:30 PM  Boise State (25) @ Notre Dame (2) 
O/U 53.50
Boise State
WIN 36.7-25.1
won 75.63% of sims, total points 61.8
Prediction
Notre Dame wins 28-7
 

3:30 PM  Washington (21) @ Maryland  
O/U 53.50
Washington
WIN 35.9-16.3
won 90.00% of sims, total points 52.2
Prediction
Washington wins 24-20
 

 
3:30 PM  James Madison @ Georgia State  
O/U 54.00
Georgia State
WIN 32.9-8.2
won 95.51% of sims, total points 41.0
Prediction
James Madison wins 14-7
 

 
3:30 PM  Texas (3) @ Florida  
O/U 53.50
Texas
WIN 18.9-18.2
won 54.06% of sims, total points 37.2
Prediction
Florida wins 29-21
 

 
3:30 PM  Syracuse @ SMU  
O/U 58.50
Syracuse
WIN 40.5-13.6
won 94.06% of sims, total points 54.1
Prediction
SMU wins 31-18
 

 
3:30 PM  UL Monroe @ Northwestern  
O/U 40.50
Northwestern
WIN 25.3-12.7
won 80.53% of sims, total points 38.0
Prediction
Northwestern wins 42-7
 

3:30 PM  Oregon State @ Appalachian State  
O/U 55.00
Oregon State
WIN 28.4-20.5
won 68.68% of sims, total points 48.9
Prediction
Appalachian State wins 27-23
 

 
3:30 PM  Penn State @ UCLA  
O/U 50.00
Penn State
WIN 25.0-19.7
won 64.06% of sims, total points 44.6
Prediction
UCLA wins 42-37
 

3:30 PM  FIU @ Connecticut  
O/U 54.50
Connecticut
WIN 46.0-10.5
won 99.38% of sims, total points 56.5
Prediction
Connecticut wins 51-10
 

 
 
3:30 PM  Miami (Ohio) @ Northern Illinois  
O/U 39.50
Miami (Ohio)
WIN 22.8-11.3
won 82.50% of sims, total points 34.1
Prediction
Miami (Ohio) wins 25-14
 

 
 
3:30 PM  Central Michigan @ Akron  
O/U 45.50
Central Michigan
WIN 24.4-12.5
won 83.44% of sims, total points 36.9
Prediction
Akron wins 28-22
 

3:30 PM  Eastern Michigan @ Buffalo  
O/U 48.50
Buffalo
WIN 22.1-19.0
won 57.81% of sims, total points 41.1
Prediction
Buffalo wins 31-30
 

 
3:30 PM  Stony Brook @ UAlbany  
Stony Brook
WIN 21.8-10.9
won 80.33% of sims, total points 32.7
Prediction
Stony Brook wins 47-12
 

3:30 PM  North Carolina A&T @ William & Mary  
William & Mary
WIN 29.8-6.1
won 97.00% of sims, total points 35.9
Prediction
William & Mary wins 38-34
 

4 PM  Kent State @ Oklahoma (17) 
O/U 53.50
Oklahoma
WIN 26.4-6.8
won 93.44% of sims, total points 33.2
Prediction
Oklahoma wins 44-0
 

 
4 PM  Michigan State @ Nebraska (15) 
O/U 53.50
Nebraska
WIN 35.0-16.2
won 91.25% of sims, total points 51.2
Prediction
Nebraska wins 38-27
 

4 PM  Texas State @ Arkansas State  
O/U 64.50
Texas State
WIN 29.8-21.0
won 71.56% of sims, total points 50.8
Prediction
Arkansas State wins 31-30
 

 
4 PM  Elon @ Towson  
Elon
WIN 21.6-17.9
won 62.00% of sims, total points 39.5
Prediction
Elon wins 17-3
 

4 PM  Samford @ Mercer  
Mercer
WIN 43.8-15.6
won 96.67% of sims, total points 59.4
Prediction
Mercer wins 42-21
 

4 PM  Nicholls State @ Lamar  
Nicholls State
WIN 21.7-7.2
won 87.00% of sims, total points 28.9
Prediction
Lamar wins 24-17
 

4 PM  Prairie View @ Alcorn State  
Prairie View
WIN 32.3-12.7
won 88.00% of sims, total points 45.0
Prediction
Prairie View wins 13-12
 

4 PM  West Georgia @ Austin Peay  
Austin Peay
WIN 31.7-12.4
won 89.00% of sims, total points 44.1
Prediction
Austin Peay wins 44-30
 

 
4 PM  Norfolk State @ Hampton  
Hampton
WIN 21.7-15.6
won 63.67% of sims, total points 37.4
Prediction
Hampton wins 41-34
 

 
5 PM  Montana State @ Northern Arizona  
Northern Arizona
WIN 29.7-25.8
won 59.67% of sims, total points 55.5
Prediction
Montana State wins 34-7
 

5 PM  Utah Tech @ Central Arkansas  
Central Arkansas
WIN 28.9-15.7
won 83.00% of sims, total points 44.6
Prediction
Central Arkansas wins 20-17
 

5 PM  North Dakota @ Northern Iowa  
North Dakota
WIN 27.7-12.8
won 82.67% of sims, total points 40.6
Prediction
North Dakota wins 28-0
 

6 PM  Coastal Carolina @ Old Dominion  
O/U 55.00
Old Dominion
WIN 47.3-9.0
won 99.69% of sims, total points 56.3
Prediction
Old Dominion wins 47-7
 

 
6 PM  South Dakota State @ Youngstown State  
Youngstown State
WIN 25.4-17.2
won 73.00% of sims, total points 42.6
Prediction
South Dakota State wins 35-24
 

6 PM  Jackson State @ Alabama A&M  
Alabama A&M
WIN 30.1-22.8
won 65.67% of sims, total points 52.9
Prediction
Jackson State wins 57-24
 

7 PM  Texas Tech (11) @ Houston  
O/U 50.00
Texas Tech
WIN 30.3-17.8
won 83.44% of sims, total points 48.1
Prediction
Texas Tech wins 35-11
 

 
7 PM  Florida Atlantic @ Rice  
O/U 52.50
Rice
WIN 19.5-17.6
won 55.63% of sims, total points 37.1
Prediction
Florida Atlantic wins 27-21
 

 
7 PM  South Alabama @ Troy  
O/U 47.50
Troy
WIN 22.8-18.1
won 61.88% of sims, total points 40.9
Prediction
Troy wins 31-24
 

 
7 PM  UNLV @ Wyoming  
O/U 53.00
Wyoming
WIN 27.4-21.2
won 65.31% of sims, total points 48.6
Prediction
UNLV wins 31-17
 

 
7 PM  Southern Utah @ Tarleton State  
Tarleton State
WIN 39.3-16.0
won 93.00% of sims, total points 55.3
Prediction
Tarleton State wins 52-42
 

7 PM  SFA @ Incarnate Word  
SFA
WIN 21.0-17.7
won 63.67% of sims, total points 38.8
Prediction
SFA wins 31-9
 

7 PM  Arkansas-Pine Bluff @ Texas Southern  
Arkansas-Pine Bluff
WIN 16.2-11.4
won 64.00% of sims, total points 27.6
Prediction
Texas Southern wins 44-0
 

7 PM  North Dakota State @ Illinois State  
North Dakota State
WIN 37.3-18.0
won 86.33% of sims, total points 55.3
Prediction
North Dakota State wins 25-16
 

7 PM  Indiana State @ Southern Illinois  
Southern Illinois
WIN 42.7-10.7
won 98.33% of sims, total points 53.5
Prediction
Southern Illinois wins 55-27
 

 
7 PM  East Texas A&M @ Northwestern State  
East Texas A&M
WIN 22.0-9.7
won 82.00% of sims, total points 31.7
Prediction
East Texas A&M wins 40-10
 

7 PM  SE Louisiana @ McNeese  
McNeese
WIN 31.1-21.2
won 74.33% of sims, total points 52.3
Prediction
SE Louisiana wins 38-0
 

7 PM  Portland State @ Eastern Washington  
Eastern Washington
WIN 18.4-16.6
won 54.33% of sims, total points 35.0
Prediction
Eastern Washington wins 35-27
 

 
7:30 PM  Mississippi State @ Texas A&M (1) 
O/U 58.00
Texas A&M
WIN 40.1-12.7
won 95.63% of sims, total points 52.8
Prediction
Texas A&M wins 31-9
 

 
 
7:30 PM  Miami (6) @ Florida State (8) 
O/U 53.50
Miami
WIN 30.8-29.9
won 52.50% of sims, total points 60.7
Prediction
Miami wins 28-22
 

 
7:30 PM  Minnesota @ Ohio State (4) 
O/U 44.50
Ohio State
WIN 46.8-11.0
won 99.38% of sims, total points 57.8
Prediction
Ohio State wins 42-3
 

 
 
7:30 PM  Colorado @ TCU  
O/U 58.00
Colorado
WIN 41.6-13.7
won 95.94% of sims, total points 55.2
Prediction
TCU wins 35-21
 

 
7:30 PM  Kansas (18) @ UCF  
O/U 55.50
Kansas
WIN 39.8-22.6
won 85.94% of sims, total points 62.4
Prediction
Kansas wins 27-20
 

8 PM  Tulsa @ Memphis  
O/U 56.50
Memphis
WIN 39.4-14.9
won 92.50% of sims, total points 54.4
Prediction
Memphis wins 45-7
 

 
8 PM  Montana @ Idaho State  
Montana
WIN 35.8-34.9
won 52.33% of sims, total points 70.6
Prediction
Montana wins 42-38
 

 
8 PM  UC Davis @ Cal Poly  
Cal Poly
WIN 29.6-26.9
won 57.33% of sims, total points 56.4
Prediction
UC Davis wins 27-20
 

10:30 PM  Duke @ California  
O/U 56.00
Duke
WIN 50.3-13.4
won 98.13% of sims, total points 63.7
Prediction
Duke wins 45-21
 

 
10:30 PM  Nevada @ Fresno State  
O/U 44.00
Fresno State
WIN 33.8-13.5
won 90.94% of sims, total points 47.3
Prediction
Fresno State wins 20-17
 

Legend/Totals

 TotalTop 25
Correct Picks 70 (67.3%)13 (76.5%)
Incorrect Picks 34 (32.7%)4 (23.5%)
Final Margin within 5 Pts 24 (23.1%)4 (23.5%)
Beat the Spread 27 (57.4%)0 (0.0%)

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