College Football Predictions for Week 16

Odds: Line |  O/U
Division: All |  FBS |  FCS |  II |  III
Postseason: Recent |  All Week 16

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9/27/2025 NCAA FB Games
Time	Matchup	Prediction	Actual	Result
12 PM	USC (22) @ Illinois   Spd: +1.5 📊 GOLD	USC WIN 41.1-18.6 won 91.05% of sims, average margin of 22.4 Prediction Projected Stats	Illinois wins 34-32
12 PM	Notre Dame (2) @ Arkansas   Spd: +10.5 📊 GOLD	Arkansas WIN 44.4-18.9 won 93.16% of sims, average margin of 25.5 Prediction Projected Stats	Notre Dame wins 56-13
12 PM	Georgia Tech (13) @ Wake Forest (14)  Spd: +17.0 📊 GOLD	Georgia Tech WIN 41.5-21.5 won 87.89% of sims, average margin of 20.0 Prediction Projected Stats	Georgia Tech wins 30-29
12 PM	Cincinnati (20) @ Kansas (18)  Spd: -6.0 📊 GOLD	Cincinnati WIN 29.7-27.0 won 58.95% of sims, average margin of 2.7 Prediction Projected Stats	Cincinnati wins 37-34
12 PM	Duke @ Syracuse   Spd: +6.5 📊 GOLD	Duke WIN 33.1-32.6 won 51.58% of sims, average margin of 0.6 Prediction Projected Stats	Duke wins 38-3
12 PM	Louisville (12) @ Pittsburgh (10)  Spd: +5.5 📊 GOLD	Louisville WIN 29.7-20.5 won 70.00% of sims, average margin of 9.2 Prediction Projected Stats	Louisville wins 34-27
12 PM	UCF @ Kansas State   Spd: -5.5 📊 GOLD	Kansas State WIN 20.8-18.9 won 56.05% of sims, average margin of 1.9 Prediction Projected Stats	Kansas State wins 34-20
12 PM	South Alabama @ North Texas   Spd: -10.5 📊 GOLD	North Texas WIN 32.6-17.7 won 83.16% of sims, average margin of 14.9 Prediction Projected Stats	North Texas wins 36-22
12 PM	Rutgers @ Minnesota   Spd: -3.5 📊 GOLD	Minnesota WIN 27.3-24.8 won 57.37% of sims, average margin of 2.5 Prediction Projected Stats	Minnesota wins 31-28
12 PM	Bowling Green @ Ohio   Spd: -10.0 📊 GOLD	Ohio WIN 29.8-21.1 won 70.26% of sims, average margin of 8.7 Prediction Projected Stats	Ohio wins 35-20
12:45 PM	Utah State @ Vanderbilt (9)  Spd: -21.5 📊 GOLD	Vanderbilt WIN 33.3-24.5 won 70.79% of sims, average margin of 8.7 Prediction Projected Stats	Vanderbilt wins 55-35
1 PM	Eastern Michigan @ Central Michigan   Spd: -4.5 📊 GOLD	Central Michigan WIN 27.9-17.1 won 76.84% of sims, average margin of 10.8 Prediction Projected Stats	Central Michigan wins 24-13
1:30 PM	Georgia Southern @ James Madison   Spd: -12.5 📊 GOLD	Georgia Southern WIN 22.9-20.2 won 56.58% of sims, average margin of 2.6 Prediction Projected Stats	James Madison wins 35-10
3 PM	Arkansas State @ UL Monroe   Spd: -1.5 📊 GOLD	Arkansas State WIN 27.8-13.3 won 84.47% of sims, average margin of 14.5 Prediction Projected Stats	UL Monroe wins 28-16
3:30 PM	LSU @ Ole Miss (16)  Spd: +2.5 📊 GOLD	Ole Miss WIN 51.3-7.3 won 100.00% of sims, average margin of 43.9 Prediction Projected Stats	Ole Miss wins 24-19
3:30 PM	Auburn @ Texas A&M (1)  Spd: -6.5 📊 GOLD	Texas A&M WIN 37.5-16.1 won 91.58% of sims, average margin of 21.4 Prediction Projected Stats	Texas A&M wins 16-10
3:30 PM	Indiana (7) @ Iowa   Spd: +3.0 📊 GOLD	Indiana WIN 44.3-6.4 won 100.00% of sims, average margin of 37.9 Prediction Projected Stats	Indiana wins 20-15
3:30 PM	Ohio State (4) @ Washington (21)  Spd: +13.5 📊 GOLD	Ohio State WIN 32.5-26.7 won 65.26% of sims, average margin of 5.8 Prediction Projected Stats	Ohio State wins 24-6
3:30 PM	Rice @ Navy   Spd: -14.0 📊 GOLD	Navy WIN 32.8-10.6 won 93.42% of sims, average margin of 22.2 Prediction Projected Stats	Navy wins 21-13
3:30 PM	San Diego State @ Northern Illinois   Spd: +2.5 📊 GOLD	Northern Illinois WIN 16.5-10.7 won 67.11% of sims, average margin of 5.9 Prediction Projected Stats	San Diego State wins 6-3
3:30 PM	Utah @ West Virginia   Spd: +12.5 📊 GOLD	West Virginia WIN 21.3-15.6 won 65.79% of sims, average margin of 5.7 Prediction Projected Stats	Utah wins 48-14
3:30 PM	UCLA @ Northwestern   Spd: -5.5 📊 GOLD	Northwestern WIN 28.4-15.7 won 80.26% of sims, average margin of 12.7 Prediction Projected Stats	Northwestern wins 17-14
3:30 PM	Baylor @ Oklahoma State   Spd: +17.5 📊 GOLD	Baylor WIN 37.9-16.8 won 91.58% of sims, average margin of 21.1 Prediction Projected Stats	Baylor wins 45-27
3:30 PM	California @ Boston College   Spd: -4.5 📊 GOLD	Boston College WIN 38.6-13.1 won 95.00% of sims, average margin of 25.5 Prediction Projected Stats	California wins 28-24
3:30 PM	Connecticut @ Buffalo   Spd: +2.5 📊 GOLD	Connecticut WIN 33.8-14.8 won 86.84% of sims, average margin of 19.0 Prediction Projected Stats	Connecticut wins 20-17
3:30 PM	Akron @ Toledo (24)  Spd: -21.0 📊 GOLD	Toledo WIN 29.5-14.3 won 82.89% of sims, average margin of 15.2 Prediction Projected Stats	Toledo wins 45-3
3:30 PM	Lindenwood @ Miami (Ohio)	Miami (Ohio) WIN 24.6-14.7 won 74.86% of sims, average margin of 9.8 Prediction Projected Stats	Miami (Ohio) wins 38-0
4 PM	Tulane @ Tulsa   Spd: +14.5 📊 GOLD	Tulane WIN 37.3-14.9 won 91.05% of sims, average margin of 22.4 Prediction Projected Stats	Tulane wins 31-14
4 PM	New Mexico State @ New Mexico   Spd: -10.0 📊 GOLD	New Mexico WIN 31.0-11.6 won 91.84% of sims, average margin of 19.4 Prediction Projected Stats	New Mexico wins 38-20
4:10 PM	Hawaii @ Air Force   Spd: -5.5 📊 GOLD	Air Force WIN 31.3-17.6 won 79.47% of sims, average margin of 13.7 Prediction Projected Stats	Hawaii wins 44-35
4:15 PM	Tennessee (23) @ Mississippi State   Spd: +10.0 📊 GOLD	Tennessee WIN 32.6-29.1 won 59.47% of sims, average margin of 3.5 Prediction Projected Stats	Tennessee wins 41-34
6 PM	Liberty @ Old Dominion   Spd: -8.5 📊 GOLD	Old Dominion WIN 50.2-7.9 won 99.47% of sims, average margin of 42.3 Prediction Projected Stats	Old Dominion wins 21-7
6 PM	Middle Tennessee @ Kennesaw State   Spd: -7.0 📊 GOLD	Kennesaw State WIN 32.6-15.4 won 84.74% of sims, average margin of 17.3 Prediction Projected Stats	Kennesaw State wins 24-16
6:30 PM	Rhode Island @ Western Michigan	Rhode Island WIN 26.9-9.1 won 88.51% of sims, average margin of 17.8 Prediction Projected Stats	Western Michigan wins 47-14
7 PM	Arizona @ Iowa State   Spd: -7.0 📊 GOLD	Iowa State WIN 20.6-20.3 won 48.68% of sims, average margin of 0.3 Prediction Projected Stats	Iowa State wins 39-14
7 PM	Virginia Tech @ NC State   Spd: -7.5 📊 GOLD	NC State WIN 37.1-18.4 won 88.16% of sims, average margin of 18.7 Prediction Projected Stats	Virginia Tech wins 23-21
7 PM	Memphis @ Florida Atlantic   Spd: +14.0 📊 GOLD	Memphis WIN 35.0-18.1 won 85.26% of sims, average margin of 17.0 Prediction Projected Stats	Memphis wins 55-26
7 PM	Jacksonville State @ Southern Miss   Spd: -2.5 📊 GOLD	Southern Miss WIN 38.3-14.5 won 91.84% of sims, average margin of 23.8 Prediction Projected Stats	Southern Miss wins 42-25
7 PM	Western Kentucky @ Missouri State   Spd: +7.0 📊 GOLD	Western Kentucky WIN 34.0-17.5 won 86.84% of sims, average margin of 16.5 Prediction Projected Stats	Western Kentucky wins 27-22
7:30 PM	Alabama @ Georgia   Spd: -4.0 📊 GOLD	Alabama WIN 47.1-13.5 won 98.42% of sims, average margin of 33.5 Prediction Projected Stats	Alabama wins 24-21
7:30 PM	Oregon @ Penn State   Spd: -6.5 📊 GOLD	Oregon WIN 24.9-23.3 won 54.21% of sims, average margin of 1.6 Prediction Projected Stats	Oregon wins 30-24
7:30 PM	Washington State @ Colorado State   Spd: -4.0 📊 GOLD	Colorado State WIN 19.9-17.3 won 58.42% of sims, average margin of 2.6 Prediction Projected Stats	Washington State wins 20-3
7:30 PM	Massachusetts @ Missouri   Spd: -42.5 📊 GOLD	Missouri WIN 53.0-5.9 won 100.00% of sims, average margin of 47.1 Prediction Projected Stats	Missouri wins 42-6
7:30 PM	Appalachian State @ Boise State (25)  Spd: -17.5 📊 GOLD	Boise State WIN 40.9-22.9 won 83.42% of sims, average margin of 18.0 Prediction Projected Stats	Boise State wins 47-14
7:30 PM	San Jose State @ Stanford   Spd: -1.5 📊 GOLD	San Jose State WIN 27.4-18.2 won 73.68% of sims, average margin of 9.1 Prediction Projected Stats	Stanford wins 30-29
7:45 PM	Kentucky @ South Carolina   Spd: -6.0 📊 GOLD	Kentucky WIN 28.4-16.8 won 79.74% of sims, average margin of 11.6 Prediction Projected Stats	South Carolina wins 35-13
8 PM	Marshall @ Louisiana   Spd: -3.5 📊 GOLD	Marshall WIN 28.6-13.3 won 83.68% of sims, average margin of 15.3 Prediction Projected Stats	Louisiana wins 54-51
9 PM	Louisiana Tech @ UTEP   Spd: +4.0 📊 GOLD	Louisiana Tech WIN 20.7-19.4 won 52.11% of sims, average margin of 1.3 Prediction Projected Stats	Louisiana Tech wins 30-11
10:15 PM	BYU (19) @ Colorado   Spd: +4.0 📊 GOLD	Colorado WIN 32.6-15.2 won 87.63% of sims, average margin of 17.4 Prediction Projected Stats	BYU wins 24-21

Legend/Totals

	Total	Top 25
Correct Picks	34 (69.4%)	11 (78.6%)
Incorrect Picks	15 (30.6%)	3 (21.4%)
Final Margin within 5 Pts	12 (24.5%)	3 (21.4%)
Beat the Spread	24 (51.1%)	8 (57.1%)