Prediction: Michigan State vs USC on 9/20/2025 | College Football Predictions - MyGameSim.com

College Football Prediction
Michigan State vs USC on 9/20/2025

See the simulated matchup results between the USC and the Michigan State powered by MyGameSim. Get predicted scores, projected player stats, and key insights from our College Football Game Simulator.

FINAL SCORE

The predicted score is USC (2026): 43.6 - Michigan State (2026): 18.4, decided by < 5 pts 33 times (8.7%)

 
MATCHUP SIMULATION STATS
USC vs. Michigan State
 

(2026)

» USC won 356 times (93.7%)

» USC won by >20 pts 231 times (60.8%)

(2026)

» Michigan State won 24 times (6.3%)

» Michigan State won by >20 pts 2 times (0.5%)

 
PROJECTED PLAYER STATS
Only Game Sim+ subscribers have access to view Projected Stats

Michigan State Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

Michigan State Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

Michigan State Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

USC Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

USC Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

USC Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

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