MLB Predictions for 9/28/2025
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Odds: Line | O/U | Money Line
| 9/28/2025 MLB Games | ||||
|---|---|---|---|---|
| Time *ET | Matchup | Prediction | Actual | Result |
| 3:05 PM |  Detroit Tigers @ Boston Red Sox  Chris Paddack vs Jose De Leon O/U 9 +/- Lineups | Boston Red Sox WIN 4.7-4.1 by 0.6Prediction | Boston Red Sox wins 4-3 |    |
| 3:05 PM |  Kansas City Royals @ Athletics  Cole Ragans vs Mitch Spence O/U 9 +/- Lineups | Kansas City Royals WIN 4.6-4.4 by 0.2Prediction | Kansas City Royals wins 9-2 | |
| 3:05 PM |  Colorado Rockies @ San Francisco Giants  McCade Brown vs Logan Webb O/U 7.5 +/- Lineups | San Francisco Giants WIN 4.6-3.7 by 0.9Prediction | San Francisco Giants wins 4-0 | |
| 3:05 PM |  Minnesota Twins @ Philadelphia Phillies  Simeon Woods Richardson vs Cristopher Sanchez O/U 8 +/- Lineups | Philadelphia Phillies WIN 4.7-3.5 by 1.2Prediction | Philadelphia Phillies wins 2-1 | |
| 3:05 PM |  Chicago White Sox @ Washington Nationals  Shane Smith vs Brad Lord O/U 8.5 +/- Lineups | Chicago White Sox WIN 4.4-3.5 by 0.9Prediction | Chicago White Sox wins 8-0 | |
| 3:05 PM |  Baltimore Orioles @ New York Yankees  Kyle Bradish vs Luis Gil O/U 8.5 +/- Lineups | New York Yankees WIN 5.2-4.9 by 0.3Prediction | New York Yankees wins 3-2 | |
| 3:07 PM |  Houston Astros @ Los Angeles Angels  Lance McCullers Jr. vs Sam Aldegheri O/U 9 +/- Lineups | Houston Astros WIN 5.6-4.4 by 1.2Prediction | Houston Astros wins 6-2 | |
| 3:07 PM |  Tampa Bay Rays @ Toronto Blue Jays  Ian Seymour vs Kevin Gausman O/U 7.5 +/- Lineups | Toronto Blue Jays WIN 3.7-3.4 by 0.3Prediction | Toronto Blue Jays wins 13-4 | |
| 3:10 PM |  Texas Rangers @ Cleveland Guardians  Patrick Corbin vs Logan Allen O/U 7.5 +/- Lineups | Texas Rangers WIN 3.7-3.3 by 0.3Prediction | Cleveland Guardians wins 9-8 |  |
| 3:10 PM |  Arizona Diamondbacks @ San Diego Padres  Brandon Pfaadt vs JP Sears O/U 8 +/- Lineups | San Diego Padres WIN 4.5-3.9 by 0.6Prediction | San Diego Padres wins 12-4 | |
| 3:10 PM |  Los Angeles Dodgers @ Seattle Mariners  Clayton Kershaw vs Bryce Miller O/U 7.5 +/- Lineups | Los Angeles Dodgers WIN 4.8-4.2 by 0.6Prediction | Los Angeles Dodgers wins 6-1 | |
| 3:10 PM |  New York Mets @ Miami Marlins  Sean Manaea vs Edward Cabrera O/U 8.5 +/- Lineups | New York Mets WIN 4.9-3.9 by 1.0Prediction | Miami Marlins wins 4-0 | |
| 3:10 PM |  Cincinnati Reds @ Milwaukee Brewers  Brady Singer vs Freddy Peralta O/U 7.5 +/- Lineups | Milwaukee Brewers WIN 4.5-4.0 by 0.6Prediction | Milwaukee Brewers wins 4-2 | |
| 3:15 PM |  Pittsburgh Pirates @ Atlanta Braves  Johan Oviedo vs Chris Sale O/U 7.5 +/- Lineups | Atlanta Braves WIN 4.4-3.1 by 1.2Prediction | Atlanta Braves wins 4-1 | |
| 3:20 PM |  St. Louis Cardinals @ Chicago Cubs  Andre Pallante vs Javier Assad O/U 7 +/- Lineups | Chicago Cubs WIN 4.6-3.3 by 1.3Prediction | Chicago Cubs wins 2-0 | |
Legend/Totals
Correct Picks  | 13 (86.7%) |
Incorrect Picks  | 2 (13.3%) |
Final Margin within 5 Runs  | 4 (26.7%) |
| Beat the Spread | 4 (26.7%) |
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