Prediction: San Francisco 49ers vs Los Angeles Rams on 10/2/2025 | NFL Predictions - MyGameSim.com

NFL Prediction
San Francisco 49ers vs Los Angeles Rams on 10/2/2025

See the simulated matchup results between the Rams and the 49ers powered by MyGameSim. Get predicted scores, projected player stats, and key insights from our NFL Game Simulator.

FINAL SCORE
Spread: Los Angeles Rams by 8.5 Over/Under: 45.5

Prediction Accuracy

Winner: Incorrect
vs Spread: Incorrect
Over/Under: Incorrect

The predicted score is Rams (2026): 24.8 - 49ers (2026): 15.0, decided by < 7 pts 172 times (20.5%)

 
MATCHUP SIMULATION STATS
Rams vs. 49ers
 

(2026)

» Rams won 629 times (74.9%)

» Rams won by >20 pts 217 times (25.8%)

(2026)

» 49ers won 211 times (25.1%)

» 49ers won by >20 pts 19 times (2.3%)

 
PROJECTED PLAYER STATS
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49ers Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

49ers Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

49ers Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

Rams Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

Rams Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

Rams Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

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