Prediction: Arizona Cardinals vs Indianapolis Colts on 10/12/2025 | NFL Predictions - MyGameSim.com

NFL Prediction
Arizona Cardinals vs Indianapolis Colts on 10/12/2025

See the simulated matchup results between the Colts and the Cardinals powered by MyGameSim. Get predicted scores, projected player stats, and key insights from our NFL Game Simulator.

FINAL SCORE
Spread: Indianapolis Colts by 6.5 Over/Under: 47.5

Prediction Accuracy

Winner: Correct
vs Spread: Correct
Over/Under: Incorrect

The predicted score is Colts (2026): 19.0 - Cardinals (2026): 15.6, decided by < 7 pts 270 times (27.6%)

 
MATCHUP SIMULATION STATS
Colts vs. Cardinals
 

(2026)

» Colts won 585 times (59.7%)

» Colts won by >20 pts 104 times (10.6%)

(2026)

» Cardinals won 395 times (40.3%)

» Cardinals won by >20 pts 43 times (4.4%)

 
PROJECTED PLAYER STATS
Only Game Sim+ subscribers have access to view Projected Stats

Cardinals Passing

PlayerATTCPYDSAVGTDINTLGRTG
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Cardinals Rushing

PlayerATTYDSAVGLGTD
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Cardinals Receiving

PlayerATTYDSAVGLGTD
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Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

Colts Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

Colts Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
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Player 4 -- -- -- -- --

Colts Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

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