Prediction: San Francisco 49ers vs Tampa Bay Buccaneers on 10/12/2025 | NFL Predictions - MyGameSim.com

NFL Prediction
San Francisco 49ers vs Tampa Bay Buccaneers on 10/12/2025

See the simulated matchup results between the Buccaneers and the 49ers powered by MyGameSim. Get predicted scores, projected player stats, and key insights from our NFL Game Simulator.

FINAL SCORE
Spread: Tampa Bay Buccaneers by 3 Over/Under: 47.5

Prediction Accuracy

Winner: Correct
vs Spread: Correct
Over/Under: Incorrect

The predicted score is Buccaneers (2026): 26.0 - 49ers (2026): 18.9, decided by < 7 pts 236 times (24.1%)

 
MATCHUP SIMULATION STATS
Buccaneers vs. 49ers
 

(2026)

» Buccaneers won 685 times (69.9%)

» Buccaneers won by >20 pts 191 times (19.5%)

(2026)

» 49ers won 295 times (30.1%)

» 49ers won by >20 pts 32 times (3.3%)

 
PROJECTED PLAYER STATS
Only Game Sim+ subscribers have access to view Projected Stats

49ers Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

49ers Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

49ers Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

Buccaneers Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

Buccaneers Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

Buccaneers Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

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