Prediction: Tennessee Titans vs San Francisco 49ers on 12/14/2025 | NFL Predictions - MyGameSim.com

NFL Prediction
Tennessee Titans vs San Francisco 49ers on 12/14/2025

See the simulated matchup results between the 49ers and the Titans powered by MyGameSim. Get predicted scores, projected player stats, and key insights from our NFL Game Simulator.

PREDICTED SCORE
Spread: San Francisco 49ers by 12.5 Over/Under: 44.5

The predicted score is 49ers (2026): 26.4 - Titans (2026): 20.3, decided by < 7 pts 50 times (31.3%)


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MATCHUP SIMULATION STATS
49ers vs. Titans
 

(2026)

» 49ers won 119 times (74.4%)

» 49ers won by >20 pts 24 times (15.0%)

(2026)

» Titans won 41 times (25.6%)

» Titans won by >20 pts 5 times (3.1%)

 
PROJECTED PLAYER STATS
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Titans Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

Titans Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

Titans Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

49ers Passing

PlayerATTCPYDSAVGTDINTLGRTG
Player 1 -- -- -- -- -- -- -- --

49ers Rushing

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --

49ers Receiving

PlayerATTYDSAVGLGTD
Player 1 -- -- -- -- --
Player 2 -- -- -- -- --
Player 3 -- -- -- -- --
Player 4 -- -- -- -- --
Player 5 -- -- -- -- --
Player 6 -- -- -- -- --

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