NFL Predictions & Game Simulator - MyGameSim.com

NFL Predictions for Week 17

Look for Jacoby Brissett (Cardinals) to have a big day. In this week's simulations he averaged 361.5 passing yards per game.
To view all of this week's player projections, you'll need a GameSim+ account.

Odds: Line |  O/U

Week 17 NFL Games
Date/TimeMatchupPredictionActualResult
9/7/2025 1 PM  Arizona Cardinals @ New Orleans Saints 
Spd: +5.5
📊 GOLD
Arizona Cardinals
WIN 21.9-19.9
won 55.64% of sims, average margin of 1.9
Prediction
Projected Stats 		Arizona Cardinals wins 20-13

 
9/14/2025 1 PM  San Francisco 49ers @ New Orleans Saints 
Spd: +3.0
📊 GOLD
San Francisco 49ers
WIN 19.5-18.0
won 54.33% of sims, average margin of 1.5
Prediction
Projected Stats 		San Francisco 49ers wins 26-21

 
9/21/2025 4:05 PM  New Orleans Saints @ Seattle Seahawks 
Spd: -7.5
📊 GOLD
Seattle Seahawks
WIN 18.1-10.4
won 71.51% of sims, average margin of 7.6
Prediction
Projected Stats 		Seattle Seahawks wins 44-13

 
9/28/2025 1 PM  New Orleans Saints @ Buffalo Bills 
Spd: -16.5
📊 GOLD
Buffalo Bills
WIN 26.8-9.5
won 90.69% of sims, average margin of 17.3
Prediction
Projected Stats 		Buffalo Bills wins 31-19

 
10/5/2025 1 PM  New York Giants @ New Orleans Saints 
Spd: -2.0
📊 GOLD
New York Giants
WIN 16.8-15.7
won 52.14% of sims, average margin of 1.1
Prediction
Projected Stats 		New Orleans Saints wins 26-14

10/12/2025 4:25 PM  New England Patriots @ New Orleans Saints 
Spd: +3.5
📊 GOLD
New England Patriots
WIN 21.8-16.6
won 63.88% of sims, average margin of 5.2
Prediction
Projected Stats 		New England Patriots wins 25-19

 
 
10/19/2025 1 PM  New Orleans Saints @ Chicago Bears 
Spd: -5.5
📊 GOLD
Chicago Bears
WIN 22.5-18.4
won 60.51% of sims, average margin of 4.1
Prediction
Projected Stats 		Chicago Bears wins 26-14

10/26/2025 4:05 PM  Tampa Bay Buccaneers @ New Orleans Saints 
Spd: +5.5
📊 GOLD
Tampa Bay Buccaneers
WIN 22.5-18.4
won 62.92% of sims, average margin of 4.1
Prediction
Projected Stats 		Tampa Bay Buccaneers wins 23-3

11/2/2025 4:05 PM  New Orleans Saints @ Los Angeles Rams 
Spd: -14.0
📊 GOLD
Los Angeles Rams
WIN 28.0-7.0
won 95.41% of sims, average margin of 20.9
Prediction
Projected Stats 		Los Angeles Rams wins 34-10

 
 
11/9/2025 1 PM  New Orleans Saints @ Carolina Panthers 
Spd: -5.5
📊 GOLD
Carolina Panthers
WIN 26.4-14.8
won 82.55% of sims, average margin of 11.6
Prediction
Projected Stats 		New Orleans Saints wins 17-7

11/23/2025 4:25 PM  Atlanta Falcons @ New Orleans Saints 
Spd: -1.5
📊 GOLD
New Orleans Saints
WIN 21.2-19.9
won 55.63% of sims, average margin of 1.3
Prediction
Projected Stats 		Atlanta Falcons wins 24-10

 
11/30/2025 1 PM  New Orleans Saints @ Miami Dolphins 
Spd: -6.0
📊 GOLD
Miami Dolphins
WIN 26.6-21.3
won 64.17% of sims, average margin of 5.3
Prediction
Projected Stats 		Miami Dolphins wins 21-17

 
 
12/7/2025 1 PM  New Orleans Saints @ Tampa Bay Buccaneers 
Spd: -8.5
📊 GOLD
Tampa Bay Buccaneers
WIN 27.4-21.7
won 67.89% of sims, average margin of 5.7
Prediction
Projected Stats 		New Orleans Saints wins 24-20

 
12/14/2025 4:25 PM  Carolina Panthers @ New Orleans Saints 
Spd: +2.5
📊 GOLD
New Orleans Saints
WIN 23.4-22.1
won 52.67% of sims, average margin of 1.3
Prediction
Projected Stats 		New Orleans Saints wins 20-17

 
 
12/21/2025 1 PM  New York Jets @ New Orleans Saints 
ML: -230 / +190Spd: -4.5O/U: 40.5
📊 GOLD
New Orleans Saints
WIN 24.9-16.7
won 75.56% of sims, average margin of 8.2
Prediction
Projected Stats 		New Orleans Saints wins 29-6

 
12/28/2025 1 PM  New Orleans Saints @ Tennessee Titans 
ML: +124 / -148Spd: +2.5O/U: 39.5
📊 GOLD
New Orleans Saints
WIN 21.6-21.1
won 51.07% of sims, average margin of 0.4
Prediction | Simulate
Projected Stats 		 

 

Legend/Totals

Correct Picks 11 (73.3%)
Incorrect Picks 4 (26.7%)
Final Margin within 7 Pts 7 (46.7%)
Beat the Spread 8 (53.3%)
Feedback