MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 9/23/2025

Look for Jorge Polanco (SEA) to have a big day. In today's simulations he homered once every 17.86 at bats.
To view all of today's player projections, you'll need a GameSim+ account.

Today's MLB Games
Time *ETMatchupPredictionActualResult
6:35 PM Tampa Bay Rays @ Baltimore Orioles  
Ryan Pepiot vs Dean Kremer
by 1.5
+/- Lineups
Baltimore Orioles
WIN 4.4-4.0
  by 0.4
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Projected Stats

 
6:40 PM Detroit Tigers @ Cleveland Guardians  
Tarik Skubal vs Gavin Williams
by 1.5
+/- Lineups
Detroit Tigers
WIN 4.1-3.2
  by 0.9
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Projected Stats

 
6:40 PM Pittsburgh Pirates @ Cincinnati Reds  
Johan Oviedo vs Brady Singer
by 1.5
+/- Lineups
Cincinnati Reds
WIN 4.2-3.6
  by 0.6
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Projected Stats

 
6:45 PM Miami Marlins @ Philadelphia Phillies  
Edward Cabrera vs Cristopher Sanchez
by 1.5
+/- Lineups
Philadelphia Phillies
WIN 5.1-4.4
  by 0.6
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Projected Stats

 
7:05 PM Chicago White Sox @ New York Yankees  
Shane Smith vs Luis Gil
by 1.5
+/- Lineups
New York Yankees
WIN 5.2-3.6
  by 1.5
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Projected Stats

 
7:07 PM Boston Red Sox @ Toronto Blue Jays  
Lucas Giolito vs Kevin Gausman
by 1.5
+/- Lineups
Toronto Blue Jays
WIN 4.8-4.0
  by 0.8
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Projected Stats

 
7:15 PM Washington Nationals @ Atlanta Braves  
Brad Lord vs Hurston Waldrep
by 1.5
+/- Lineups
Atlanta Braves
WIN 5.5-3.9
  by 1.6
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Projected Stats

 
7:40 PM New York Mets @ Chicago Cubs  
David Peterson vs Cade Horton
by 1.5
+/- Lineups
New York Mets
WIN 4.2-3.7
  by 0.5
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Projected Stats

 
8:05 PM Minnesota Twins @ Texas Rangers  
Zebby Matthews vs Patrick Corbin
by 1.5
+/- Lineups
Texas Rangers
WIN 4.2-3.2
  by 1.0
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Projected Stats

 
9:38 PM Kansas City Royals @ Los Angeles Angels  
Cole Ragans vs Sam Aldegheri
by 1.5
Los Angeles Angels
WIN 4.9-4.1
  by 0.8
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Projected Stats

 
9:40 PM Los Angeles Dodgers @ Arizona Diamondbacks  
Shohei Ohtani vs Brandon Pfaadt
by 1.5
+/- Lineups
Los Angeles Dodgers
WIN 4.9-4.1
  by 0.8
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Projected Stats

 
9:40 PM Colorado Rockies @ Seattle Mariners  
McCade Brown vs Bryce Miller
by 1.5
Seattle Mariners
WIN 5.7-4.0
  by 1.7
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Projected Stats

 
9:40 PM Milwaukee Brewers @ San Diego Padres  
Bruce Zimmermann vs Randy Vasquez
by 1.5
Milwaukee Brewers
WIN 4.7-4.6
  by 0.1
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Projected Stats

 
9:45 PM St. Louis Cardinals @ San Francisco Giants  
Andre Pallante vs Logan Webb
by 1.5
San Francisco Giants
WIN 4.9-4.2
  by 0.7
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Projected Stats

 
10:05 PM Houston Astros @ Athletics  
Cristian Javier vs Jeffrey Springs
by 1.5
Athletics
WIN 5.3-4.9
  by 0.4
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Projected Stats

 

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