MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 9/20/2025


9/20/2025 MLB Games
Time *ETMatchupPredictionActualResult
1:10 PM Atlanta Braves @ Detroit Tigers  
Joey Wentz vs Keider Montero
by 1.5
+/- Lineups
Detroit Tigers
WIN 5.0-4.8
  by 0.2
Prediction
Atlanta Braves wins 6-5

 
2:10 PM Cleveland Guardians @ Minnesota Twins  
Slade Cecconi vs Joe Ryan
by 1.5
+/- Lineups
Minnesota Twins
WIN 4.1-3.6
  by 0.6
Prediction
Cleveland Guardians wins 6-0

4:10 PM Washington Nationals @ New York Mets  
Cade Cavalli vs Nolan McLean
by 1.5
+/- Lineups
New York Mets
WIN 5.3-3.1
  by 2.3
Prediction
Washington Nationals wins 5-3

6:40 PM Athletics @ Pittsburgh Pirates  
Luis Morales vs Bubba Chandler
by 1.5
+/- Lineups
Athletics
WIN 4.7-3.4
  by 1.2
Prediction
Pittsburgh Pirates wins 2-0

 
6:40 PM Chicago Cubs @ Cincinnati Reds  
Javier Assad vs Zack Littell
by 1.5
+/- Lineups
Cincinnati Reds
WIN 4.7-4.4
  by 0.2
Prediction
Cincinnati Reds wins 6-3

 
7:05 PM Boston Red Sox @ Tampa Bay Rays  
Kyle Harrison vs Adrian Houser
by 1.5
+/- Lineups
Boston Red Sox
WIN 5.1-3.7
  by 1.3
Prediction
Boston Red Sox wins 6-3

7:05 PM Miami Marlins @ Texas Rangers  
Adam Mazur vs Jack Leiter
by 1.5
+/- Lineups
Miami Marlins
WIN 3.9-3.9
  by 0.1
Prediction
Miami Marlins wins 4-3

 
 
7:05 PM New York Yankees @ Baltimore Orioles  
Carlos Rodon vs Tomoyuki Sugano
by 1.5
+/- Lineups
New York Yankees
WIN 5.8-3.6
  by 2.2
Prediction
New York Yankees wins 6-1

 
7:10 PM Seattle Mariners @ Houston Astros  
George Kirby vs Framber Valdez
by 1.5
+/- Lineups
Houston Astros
WIN 4.2-4.1
  by 0.0
Prediction
Seattle Mariners wins 6-4

7:10 PM San Diego Padres @ Chicago White Sox  
Yu Darvish vs Yoendrys Gomez
by 1.5
+/- Lineups
San Diego Padres
WIN 4.5-3.8
  by 0.7
Prediction
San Diego Padres wins 7-3

7:10 PM Toronto Blue Jays @ Kansas City Royals  
Shane Bieber vs Noah Cameron
by 1.5
+/- Lineups
Toronto Blue Jays
WIN 4.3-4.0
  by 0.3
Prediction
Kansas City Royals wins 2-1

 
7:10 PM Cleveland Guardians @ Minnesota Twins  
Logan Allen vs Bailey Ober
by 1.5
+/- Lineups
Cleveland Guardians
WIN 4.2-3.9
  by 0.4
Prediction
Cleveland Guardians wins 8-0

7:15 PM Milwaukee Brewers @ St. Louis Cardinals  
Chad Patrick vs Miles Mikolas
by 1.5
+/- Lineups
Milwaukee Brewers
WIN 4.7-3.9
  by 0.9
Prediction
Milwaukee Brewers wins 3-2

 
 
8:10 PM Philadelphia Phillies @ Arizona Diamondbacks  
Aaron Nola vs Zac Gallen
by 1.5
+/- Lineups
Arizona Diamondbacks
WIN 5.1-4.5
  by 0.6
Prediction
Arizona Diamondbacks wins 4-3

 
 
8:10 PM Los Angeles Angels @ Colorado Rockies  
Kyle Hendricks vs German Marquez
by 1.5
+/- Lineups
Los Angeles Angels
WIN 5.0-4.1
  by 0.9
Prediction
Los Angeles Angels wins 3-0

9:10 PM San Francisco Giants @ Los Angeles Dodgers  
Kai-Wei Teng vs Tyler Glasnow
by 1.5
+/- Lineups
Los Angeles Dodgers
WIN 5.4-3.7
  by 1.8
Prediction
Los Angeles Dodgers wins 7-5

 
 

Legend/Totals

Correct Picks 10 (62.5%)
Incorrect Picks 6 (37.5%)
Final Margin within 5 Runs 4 (25.0%)
Beat the Spread 9 (56.3%)

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