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The MLB Game Simulator uses at-bat-by-at-bat modeling, pitcher data, and player stats to predict outcomes, scores, and performances.

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Yes. Baseball predictions and player stat projections are updated daily to reflect pitching matchups, lineups, and recent performance.

How accurate are the MLB predictions?

Accuracy varies by day and matchup. We publish performance summaries so you can track results over time.

How often are predictions refreshed?

Predictions refresh daily and may update during the day when key injuries or depth chart changes occur.

MLB Predictions for 5/21/2025

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Odds: Line | O/U | Money Line

5/21/2025 MLB Games
Time *ET	Matchup	Prediction	Actual	Result
12:35 PM	Cincinnati Reds @ Pittsburgh Pirates Brady Singer vs Andrew Heaney O/U 8 +/- Lineups TJ Friedl CF Santiago Espinal 3B Elly De La Cruz SS Austin Hays DH Spencer Steer 1B Tyler Stephenson C Connor Joe LF Matt McLain 2B Rece Hinds RF Brady Singer P Oneil Cruz CF Isiah Kiner-Falefa SS Bryan Reynolds DH Spencer Horwitz 1B Alexander Canario RF Ke'Bryan Hayes 3B Adam Frazier 2B Tommy Pham LF Henry Davis C Andrew Heaney P	Cincinnati Reds WIN 3.2-3.2 by 0.0 Prediction	Pittsburgh Pirates wins 3-1
1:10 PM	Cleveland Guardians @ Minnesota Twins Logan Allen vs Bailey Ober O/U 7.5 +/- Lineups Steven Kwan LF Angel Martinez 2B Jose Ramirez 3B Kyle Manzardo DH Carlos Santana 1B Nolan Jones CF Gabriel Arias SS Bo Naylor C Will Brennan RF Logan Allen P Ryan Jeffers C Brooks Lee SS Royce Lewis DH Ty France 1B Trevor Larnach LF Jonah Bride 3B Carson McCusker RF Harrison Bader CF Willi Castro 2B Bailey Ober P	Cleveland Guardians WIN 3.4-2.5 by 0.8 Prediction	Minnesota Twins wins 6-5
1:10 PM	Houston Astros @ Tampa Bay Rays Hunter Brown vs Taj Bradley O/U 8.5 +/- Lineups Jeremy Pena SS Isaac Paredes 3B Jose Altuve DH Yainer Diaz C Christian Walker 1B Jake Meyers CF Cam Smith RF Brendan Rodgers 2B Mauricio Dubon LF Hunter Brown P Yandy Diaz DH Josh Lowe RF Brandon Lowe 2B Jonathan Aranda 1B Jose Caballero SS Chandler Simpson LF Kameron Misner CF Curtis Mead 3B Ben Rortvedt C Taj Bradley P	Houston Astros WIN 4.0-2.8 by 1.2 Prediction	Tampa Bay Rays wins 8-4
1:10 PM	Chicago Cubs @ Miami Marlins Cade Horton vs Max Meyer O/U 9 +/- Lineups Ian Happ LF Kyle Tucker DH Seiya Suzuki RF Pete Crow-Armstrong CF Michael Busch 1B Dansby Swanson SS Nico Hoerner 2B Miguel Amaya C Matt Shaw 3B Cade Horton P Jesus Sanchez RF Agustin Ramirez C Eric Wagaman 1B Kyle Stowers LF Otto Lopez SS Connor Norby 3B Matt Mervis DH Graham Pauley 2B Derek Hill CF Max Meyer P	Chicago Cubs WIN 4.5-4.5 by 0.0 Prediction	Chicago Cubs wins 2-1
1:10 PM	Baltimore Orioles @ Milwaukee Brewers Tomoyuki Sugano vs Chad Patrick O/U 8.5 +/- Lineups Jackson Holliday 2B Adley Rutschman C Gunnar Henderson SS Ryan Mountcastle DH Ryan O'Hearn 1B Cedric Mullins CF Emmanuel Rivera 3B Heston Kjerstad LF Dylan Carlson RF Tomoyuki Sugano P Brice Turang 2B Jackson Chourio CF Christian Yelich DH Rhys Hoskins 1B Sal Frelick RF Eric Haase C Jake Bauers LF Caleb Durbin 3B Joey Ortiz SS Chad Patrick P	Baltimore Orioles WIN 4.5-3.7 by 0.8 Prediction	Baltimore Orioles wins 8-4
1:15 PM	Detroit Tigers @ St. Louis Cardinals Brant Hurter vs Andre Pallante O/U 9 +/- Lineups Kerry Carpenter DH Justyn-Henry Malloy RF Zach McKinstry 3B Riley Greene LF Spencer Torkelson 1B Colt Keith 2B Dillon Dingler C Trey Sweeney SS Javier Baez CF Brant Hurter P Masyn Winn SS Brendan Donovan LF Willson Contreras DH Ivan Herrera C Alec Burleson 1B Nolan Arenado 3B Nolan Gorman 2B Jordan Walker RF Victor Scott CF Andre Pallante P	Detroit Tigers WIN 4.5-3.8 by 0.7 Prediction	Detroit Tigers wins 5-1
2:10 PM	Seattle Mariners @ Chicago White Sox Logan Evans vs Shane Smith O/U 8.5 +/- Lineups J.P. Crawford SS Jorge Polanco DH Julio Rodriguez CF Cal Raleigh C Randy Arozarena LF Rowdy Tellez 1B Leody Taveras RF Dylan Moore 2B Ben Williamson 3B Logan Evans P Chase Meidroth SS Miguel Vargas 3B Matt Thaiss C Luis Robert CF Lenyn Sosa 2B Joshua Palacios RF Andrew Vaughn DH Tim Elko 1B Josh Rojas LF Shane Smith P	Seattle Mariners WIN 4.2-3.9 by 0.4 Prediction	Seattle Mariners wins 6-5
3:45 PM	Kansas City Royals @ San Francisco Giants Daniel Lynch vs Logan Webb O/U 7.5 +/- Lineups Maikel Garcia 3B Bobby Witt SS Vinnie Pasquantino DH Salvador Perez 1B Mark Canha LF Drew Waters RF Freddy Fermin C Michael Massey 2B Kyle Isbel CF Daniel Lynch P Heliot Ramos LF Matt Chapman 3B Jung Hoo Lee CF Wilmer Flores DH Willy Adames SS Mike Yastrzemski RF Tyler Fitzgerald 2B Patrick Bailey C LaMonte Wade 1B Logan Webb P	San Francisco Giants WIN 3.4-3.2 by 0.1 Prediction	Kansas City Royals wins 8-4
3:55 PM	Cleveland Guardians @ Minnesota Twins Gavin Williams vs Chris Paddack O/U 7.5 +/- Lineups Steven Kwan LF Angel Martinez CF Jose Ramirez 3B Kyle Manzardo 1B Carlos Santana DH Daniel Schneemann 2B Gabriel Arias SS Nolan Jones RF Austin Hedges C Gavin Williams P Ryan Jeffers DH Brooks Lee SS Royce Lewis 3B Kody Clemens 2B Jonah Bride 1B Harrison Bader LF Willi Castro RF DaShawn Keirsey CF Christian Vazquez C Chris Paddack P	Cleveland Guardians WIN 3.7-3.6 by 0.1 Prediction	Cleveland Guardians wins 5-1
6:45 PM	New York Mets @ Boston Red Sox Tylor Megill vs Garrett Crochet O/U 7 +/- Lineups Francisco Lindor SS Starling Marte LF Juan Soto RF Pete Alonso 1B Mark Vientos DH Luis Torrens C Tyrone Taylor CF Luisangel Acuna 2B Brett Baty 3B Tylor Megill P Jarren Duran LF Rafael Devers DH Alex Bregman 3B Wilyer Abreu RF Kristian Campbell 2B Nick Sogard 1B Trevor Story SS Carlos Narvaez C Ceddanne Rafaela CF Garrett Crochet P	Boston Red Sox WIN 3.4-2.9 by 0.5 Prediction	New York Mets wins 5-1
6:45 PM	Atlanta Braves @ Washington Nationals AJ Smith-Shawver vs Trevor Williams O/U 8.5 +/- Lineups Alex Verdugo LF Austin Riley 3B Matt Olson 1B Marcell Ozuna DH Drake Baldwin C Ozzie Albies 2B Eli White RF Michael Harris CF Nick Allen SS AJ Smith-Shawver P CJ Abrams SS James Wood LF Nathaniel Lowe 1B Keibert Ruiz C Luis Garcia 2B Josh Bell DH Robert Hassell CF Alex Call RF Jose Tena 3B Trevor Williams P	Atlanta Braves WIN 4.6-3.8 by 0.7 Prediction \| Simulate	Postponed
7:05 PM	Texas Rangers @ New York Yankees Jacob deGrom vs Ryan Yarbrough O/U 7.5 +/- Lineups Sam Haggerty CF Wyatt Langford LF Josh Jung 3B Adolis Garcia RF Marcus Semien 2B Jonah Heim C Jake Burger 1B Kyle Higashioka DH Josh Smith SS Jacob deGrom P Trent Grisham CF Ben Rice 1B Aaron Judge DH Cody Bellinger RF Jasson Dominguez LF Anthony Volpe SS Austin Wells C DJ LeMahieu 2B Jorbit Vivas 3B Ryan Yarbrough P	New York Yankees WIN 3.7-2.9 by 0.7 Prediction	New York Yankees wins 4-3
7:07 PM	San Diego Padres @ Toronto Blue Jays Randy Vasquez vs Kevin Gausman O/U 9 +/- Lineups Fernando Tatis RF Luis Arraez 1B Manny Machado 3B Jackson Merrill CF Xander Bogaerts SS Gavin Sheets DH Jake Cronenworth 2B Jason Heyward LF Martin Maldonado C Randy Vasquez P Bo Bichette SS Vladimir Guerrero 1B Daulton Varsho CF George Springer RF Alejandro Kirk C Anthony Santander DH Addison Barger 3B Ernie Clement 2B Nathan Lukes LF Kevin Gausman P	San Diego Padres WIN 4.1-3.9 by 0.1 Prediction	Toronto Blue Jays wins 14-0
8:40 PM	Philadelphia Phillies @ Colorado Rockies Taijuan Walker vs Carson Palmquist O/U 11.5 +/- Lineups Trea Turner SS Bryce Harper 1B Kyle Schwarber DH Nick Castellanos RF J.T. Realmuto C Alec Bohm 3B Edmundo Sosa 2B Weston Wilson LF Johan Rojas CF Taijuan Walker P Jordan Beck LF Ezequiel Tovar SS Hunter Goodman C Ryan McMahon 3B Brenton Doyle CF Mickey Moniak RF Kyle Farmer 1B Nick Martini DH Adael Amador 2B Carson Palmquist P	Philadelphia Phillies WIN 3.9-3.3 by 0.6 Prediction	Philadelphia Phillies wins 9-5
10:05 PM	Los Angeles Angels @ Athletics Jack Kochanowicz vs JP Sears O/U 10.5 +/- Lineups Zach Neto SS Luis Rengifo 3B Taylor Ward LF Jorge Soler DH Logan O'Hoppe C Jo Adell RF Matthew Lugo CF Kevin Newman 1B Tim Anderson 2B Jack Kochanowicz P Lawrence Butler RF Shea Langeliers C Tyler Soderstrom LF Brent Rooker DH Miguel Andujar 3B Nick Kurtz 1B Luis Urias 2B Seth Brown CF Max Schuemann SS JP Sears P	Athletics WIN 5.1-3.1 by 2.0 Prediction	Los Angeles Angels wins 10-5
10:10 PM	Arizona Diamondbacks @ Los Angeles Dodgers Corbin Burnes vs Dustin May O/U 9.5 +/- Lineups Corbin Carroll RF Ketel Marte 2B Gabriel Moreno C Josh Naylor 1B Eugenio Suarez 3B Pavin Smith DH Geraldo Perdomo SS Alek Thomas CF Tim Tawa LF Corbin Burnes P Shohei Ohtani DH Mookie Betts SS Freddie Freeman 1B Teoscar Hernandez RF Andy Pages LF Max Muncy 3B Tommy Edman CF Dalton Rushing C Miguel Rojas 2B Dustin May P	Arizona Diamondbacks WIN 6.0-5.1 by 1.0 Prediction	Los Angeles Dodgers wins 3-1

Legend/Totals

Correct Picks	7 (46.7%)
Incorrect Picks	8 (53.3%)
Final Margin within 5 Runs	3 (20.0%)
Beat the Spread	5 (33.3%)

MLB Predictions for 5/21/2025

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