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The MLB Game Simulator uses at-bat-by-at-bat modeling, pitcher data, and player stats to predict outcomes, scores, and performances.

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Yes. Baseball predictions and player stat projections are updated daily to reflect pitching matchups, lineups, and recent performance.

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Accuracy varies by day and matchup. We publish performance summaries so you can track results over time.

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Predictions refresh daily and may update during the day when key injuries or depth chart changes occur.

MLB Predictions for 6/22/2025

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Odds: Line | O/U | Money Line

6/22/2025 MLB Games
Time *ET	Matchup	Prediction	Actual	Result
11:35 AM	Baltimore Orioles @ New York Yankees Dean Kremer vs Will Warren O/U 10 +/- Lineups Jackson Holliday 2B Ramon Urias 3B Gunnar Henderson SS Ryan O'Hearn 1B Ramon Laureano DH Colton Cowser LF Cedric Mullins CF Dylan Carlson RF Maverick Handley C Dean Kremer P Trent Grisham CF Aaron Judge RF Ben Rice 1B Cody Bellinger LF Giancarlo Stanton DH Jazz Chisholm 3B DJ LeMahieu 2B Austin Wells C Oswald Peraza SS Will Warren P	New York Yankees WIN 7.1-5.4 by 1.6 Prediction	New York Yankees wins 4-2
12:10 PM	Detroit Tigers @ Tampa Bay Rays Casey Mize vs Zack Littell O/U 8.5 +/- Lineups Colt Keith 3B Gleyber Torres 2B Kerry Carpenter DH Riley Greene LF Spencer Torkelson 1B Wenceel Perez RF Dillon Dingler C Parker Meadows CF Javier Baez SS Casey Mize P Yandy Diaz DH Brandon Lowe 2B Junior Caminero 3B Jonathan Aranda 1B Jake Mangum CF Josh Lowe RF Jose Caballero SS Matt Thaiss C Christopher Morel LF Zack Littell P	Tampa Bay Rays WIN 4.9-4.8 by 0.1 Prediction	Detroit Tigers wins 9-3
1:35 PM	Texas Rangers @ Pittsburgh Pirates Jack Leiter vs Bailey Falter O/U 9.5 +/- Lineups Sam Haggerty LF Wyatt Langford CF Corey Seager SS Marcus Semien 2B Adolis Garcia RF Jonah Heim C Josh Smith DH Josh Jung 3B Ezequiel Duran 1B Jack Leiter P Oneil Cruz CF Andrew McCutchen DH Bryan Reynolds RF Spencer Horwitz 1B Nick Gonzales 2B Joey Bart C Adam Frazier LF Ke'Bryan Hayes 3B Isiah Kiner-Falefa SS Bailey Falter P	Pittsburgh Pirates WIN 4.5-3.8 by 0.7 Prediction	Pittsburgh Pirates wins 8-3
1:37 PM	Chicago White Sox @ Toronto Blue Jays Adrian Houser vs Chris Bassitt O/U 8.5 +/- Lineups Chase Meidroth SS Andrew Benintendi LF Miguel Vargas 1B Kyle Teel C Luis Robert CF Ryan Noda DH Lenyn Sosa 2B Josh Rojas 3B Michael Taylor RF Adrian Houser P Bo Bichette SS Addison Barger 3B Vladimir Guerrero DH Alejandro Kirk C Nathan Lukes RF Ernie Clement 1B Andres Gimenez 2B Myles Straw CF Alan Roden LF Chris Bassitt P	Toronto Blue Jays WIN 3.6-3.3 by 0.3 Prediction	Chicago White Sox wins 4-2
1:40 PM	Atlanta Braves @ Miami Marlins Bryce Elder vs Sandy Alcantara O/U 8.5 +/- Lineups Ronald Acuna RF Matt Olson 1B Austin Riley 3B Marcell Ozuna DH Drake Baldwin C Ozzie Albies 2B Alex Verdugo LF Michael Harris CF Nick Allen SS Bryce Elder P Xavier Edwards 2B Jesus Sanchez RF Otto Lopez SS Eric Wagaman 1B Kyle Stowers LF Dane Myers CF Liam Hicks DH Nick Fortes C Javier Sanoja 3B Sandy Alcantara P	Atlanta Braves WIN 4.6-3.8 by 0.8 Prediction	Miami Marlins wins 5-3
2:10 PM	Milwaukee Brewers @ Minnesota Twins Quinn Priester vs David Festa O/U 9.5 +/- Lineups Sal Frelick RF Jackson Chourio CF Christian Yelich DH William Contreras C Isaac Collins LF Rhys Hoskins 1B Brice Turang 2B Caleb Durbin 3B Joey Ortiz SS Quinn Priester P Byron Buxton CF Matt Wallner RF Trevor Larnach DH Ty France 1B Brooks Lee 3B Carlos Correa SS Kody Clemens 2B Ryan Jeffers C DaShawn Keirsey LF David Festa P	Milwaukee Brewers WIN 4.8-4.4 by 0.4 Prediction	Milwaukee Brewers wins 9-8
2:15 PM	Cincinnati Reds @ St. Louis Cardinals Andrew Abbott vs Miles Mikolas O/U 9.5 +/- Lineups TJ Friedl CF Matt McLain 2B Elly De La Cruz SS Tyler Stephenson DH Gavin Lux 3B Spencer Steer 1B Will Benson LF Jose Trevino C Jake Fraley RF Andrew Abbott P Brendan Donovan DH Masyn Winn SS Alec Burleson LF Willson Contreras 1B Nolan Arenado 3B Thomas Saggese 2B Yohel Pozo C Jordan Walker RF Jose Barrero CF Miles Mikolas P	Cincinnati Reds WIN 6.5-4.3 by 2.2 Prediction	Cincinnati Reds wins 4-1
2:20 PM	Seattle Mariners @ Chicago Cubs Logan Gilbert vs Colin Rea O/U 11.5 +/- Lineups J.P. Crawford SS Julio Rodriguez CF Cal Raleigh DH Jorge Polanco 2B Randy Arozarena LF Mitch Garver C Donovan Solano 1B Dominic Canzone RF Miles Mastrobuoni 3B Logan Gilbert P Ian Happ LF Kyle Tucker DH Seiya Suzuki RF Pete Crow-Armstrong CF Michael Busch 1B Nico Hoerner SS Matt Shaw 3B Reese McGuire C Vidal Brujan 2B Colin Rea P	Seattle Mariners WIN 6.5-4.5 by 2.0 Prediction	Seattle Mariners wins 14-6
3:10 PM	Arizona Diamondbacks @ Colorado Rockies Brandon Pfaadt vs Antonio Senzatela O/U 12.5 +/- Lineups Geraldo Perdomo SS Ildemaro Vargas 2B Pavin Smith DH Josh Naylor 1B Eugenio Suarez 3B Randal Grichuk RF Tim Tawa LF Alek Thomas CF Jose Herrera C Brandon Pfaadt P Tyler Freeman DH Mickey Moniak RF Jordan Beck LF Ryan McMahon 3B Michael Toglia 1B Brenton Doyle CF Kyle Farmer 2B Braxton Fulford C Ryan Ritter SS Antonio Senzatela P	Arizona Diamondbacks WIN 7.6-5.6 by 2.1 Prediction	Colorado Rockies wins 4-2
4:05 PM	Cleveland Guardians @ Athletics Slade Cecconi vs JP Sears O/U 9 +/- Lineups Steven Kwan LF Lane Thomas CF Jose Ramirez 3B David Fry DH Kyle Manzardo 1B Angel Martinez 2B Gabriel Arias SS Nolan Jones RF Austin Hedges C Slade Cecconi P Lawrence Butler RF Jacob Wilson SS Brent Rooker DH Nick Kurtz 1B Luis Urias 2B Tyler Soderstrom LF Gio Urshela 3B Willie MacIver C Denzel Clarke CF JP Sears P	Athletics WIN 4.7-3.7 by 1.0 Prediction	Cleveland Guardians wins 3-0
4:05 PM	Boston Red Sox @ San Francisco Giants Lucas Giolito vs Robbie Ray O/U 7 +/- Lineups Rob Refsnyder DH Roman Anthony RF Romy Gonzalez 2B Carlos Narvaez C Jarren Duran LF Trevor Story SS Abraham Toro 1B Ceddanne Rafaela CF Nate Eaton 3B Lucas Giolito P Mike Yastrzemski RF Rafael Devers DH Heliot Ramos LF Wilmer Flores 1B Jung Hoo Lee CF Willy Adames SS Casey Schmitt 3B Patrick Bailey C Tyler Fitzgerald 2B Robbie Ray P	San Francisco Giants WIN 4.9-4.6 by 0.3 Prediction	San Francisco Giants wins 9-5
4:07 PM	Houston Astros @ Los Angeles Angels Ryan Gusto vs Kyle Hendricks O/U 8.5 +/- Lineups Jeremy Pena DH Jake Meyers CF Jose Altuve 2B Cam Smith RF Christian Walker 1B Victor Caratini C Cooper Hummel LF Mauricio Dubon SS Luis Guillorme 3B Ryan Gusto P Luis Rengifo 3B Nolan Schanuel 1B Mike Trout DH Taylor Ward LF Logan O'Hoppe C Jo Adell CF LaMonte Wade RF Kevin Newman SS Christian Moore 2B Kyle Hendricks P	Los Angeles Angels WIN 4.5-4.4 by 0.2 Prediction	Houston Astros wins 8-7
4:10 PM	Washington Nationals @ Los Angeles Dodgers Michael Soroka vs Ben Casparius O/U 9.5 +/- Lineups CJ Abrams SS James Wood LF Luis Garcia 2B Nathaniel Lowe 1B Josh Bell DH Brady House 3B Daylen Lile RF Keibert Ruiz C Jacob Young CF Michael Soroka P Shohei Ohtani DH Mookie Betts SS Freddie Freeman 1B Max Muncy 3B Andy Pages RF Tommy Edman 2B Hyeseong Kim CF Michael Conforto LF Dalton Rushing C Ben Casparius P	Los Angeles Dodgers WIN 5.2-3.5 by 1.8 Prediction	Los Angeles Dodgers wins 13-7
4:10 PM	Kansas City Royals @ San Diego Padres Seth Lugo vs Randy Vasquez O/U 8.5 +/- Lineups Jonathan India 2B Bobby Witt SS Maikel Garcia 3B Vinnie Pasquantino 1B Salvador Perez DH Jac Caglianone RF Drew Waters LF Freddy Fermin C Kyle Isbel CF Seth Lugo P Fernando Tatis RF Jackson Merrill CF Manny Machado 3B Luis Arraez 1B Gavin Sheets DH Xander Bogaerts SS Jake Cronenworth 2B Tyler Wade LF Martin Maldonado C Randy Vasquez P	San Diego Padres WIN 4.1-3.8 by 0.3 Prediction	San Diego Padres wins 3-2
7:10 PM	New York Mets @ Philadelphia Phillies David Peterson vs Jesus Luzardo O/U 8.5 +/- Lineups Francisco Lindor SS Starling Marte DH Juan Soto RF Pete Alonso 1B Brandon Nimmo LF Luis Torrens C Tyrone Taylor CF Ronny Mauricio 3B Luisangel Acuna 2B David Peterson P Trea Turner SS Kyle Schwarber DH Alec Bohm 3B Nick Castellanos RF J.T. Realmuto C Otto Kemp LF Edmundo Sosa 2B Buddy Kennedy 1B Johan Rojas CF Jesus Luzardo P	New York Mets WIN 5.7-4.4 by 1.3 Prediction	Philadelphia Phillies wins 7-1

Legend/Totals

Correct Picks	8 (53.3%)
Incorrect Picks	7 (46.7%)
Final Margin within 5 Runs	4 (26.7%)
Beat the Spread	7 (46.7%)

MLB Predictions for 6/22/2025

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