MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 9/12/2025


9/12/2025 MLB Games
Time *ETMatchupPredictionActualResult
2:20 PM Tampa Bay Rays @ Chicago Cubs  
Shane Baz vs Matthew Boyd
O/U 7
+/- Lineups
Chicago Cubs
WIN 4.3-3.2
  by 1.0
Prediction
Chicago Cubs wins 6-4

 
 
6:45 PM Pittsburgh Pirates @ Washington Nationals  
Mitch Keller vs Brad Lord
O/U 8.5
+/- Lineups
Washington Nationals
WIN 4.1-3.6
  by 0.5
Prediction
Washington Nationals wins 6-5

 
6:45 PM Kansas City Royals @ Philadelphia Phillies  
Michael Lorenzen vs Walker Buehler
O/U 9
+/- Lineups
Philadelphia Phillies
WIN 4.7-4.4
  by 0.3
Prediction
Philadelphia Phillies wins 8-2

 
7:07 PM Baltimore Orioles @ Toronto Blue Jays  
Trevor Rogers vs Chris Bassitt
O/U 7.5
+/- Lineups
Baltimore Orioles
WIN 4.6-3.5
  by 1.0
Prediction
Toronto Blue Jays wins 6-1

7:10 PM Texas Rangers @ New York Mets  
Jacob deGrom vs Jonah Tong
O/U 7.5
+/- Lineups
New York Mets
WIN 4.3-3.7
  by 0.6
Prediction
Texas Rangers wins 8-3

 
7:10 PM Chicago White Sox @ Cleveland Guardians  
Martin Perez vs Tanner Bibee
O/U 7.5
+/- Lineups
Chicago White Sox
WIN 4.2-3.2
  by 0.9
Prediction
Cleveland Guardians wins 4-0

 
7:10 PM New York Yankees @ Boston Red Sox  
Luis Gil vs Lucas Giolito
O/U 8.5
+/- Lineups
New York Yankees
WIN 5.7-4.6
  by 1.2
Prediction
New York Yankees wins 4-1

7:10 PM Detroit Tigers @ Miami Marlins  
Tarik Skubal vs Sandy Alcantara
O/U 7
+/- Lineups
Detroit Tigers
WIN 4.3-3.4
  by 1.0
Prediction
Miami Marlins wins 8-2

 
7:15 PM Houston Astros @ Atlanta Braves  
AJ Blubaugh vs Hurston Waldrep
O/U 8.5
+/- Lineups
Atlanta Braves
WIN 4.3-3.7
  by 0.6
Prediction
Houston Astros wins 11-3

8:10 PM Arizona Diamondbacks @ Minnesota Twins  
Brandon Pfaadt vs Pablo Lopez
O/U 8.5
+/- Lineups
Minnesota Twins
WIN 5.0-4.0
  by 1.0
Prediction
Minnesota Twins wins 9-8

 
 
8:10 PM St. Louis Cardinals @ Milwaukee Brewers  
Andre Pallante vs Quinn Priester
O/U 8.5
+/- Lineups
Milwaukee Brewers
WIN 4.6-3.8
  by 0.9
Prediction
Milwaukee Brewers wins 8-2

9:40 PM Colorado Rockies @ San Diego Padres  
Tanner Gordon vs JP Sears
O/U 8.5
+/- Lineups
San Diego Padres
WIN 5.2-4.4
  by 0.8
Prediction
Colorado Rockies wins 4-2

10:05 PM Cincinnati Reds @ Athletics  
Brady Singer vs J.T. Ginn
O/U 10.5
+/- Lineups
Athletics
WIN 4.5-4.4
  by 0.1
Prediction
Athletics wins 3-0

 
10:10 PM Los Angeles Angels @ Seattle Mariners  
Yusei Kikuchi vs Luis Castillo
O/U 7.5
+/- Lineups
Los Angeles Angels
WIN 4.4-4.3
  by 0.1
Prediction
Seattle Mariners wins 2-1

10:15 PM Los Angeles Dodgers @ San Francisco Giants  
Yoshinobu Yamamoto vs Justin Verlander
O/U 7.5
+/- Lineups
Los Angeles Dodgers
WIN 5.3-3.8
  by 1.5
Prediction
San Francisco Giants wins 5-1

Legend/Totals

Correct Picks 7 (46.7%)
Incorrect Picks 8 (53.3%)
Final Margin within 5 Runs 3 (20.0%)
Beat the Spread 7 (46.7%)

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