MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 9/19/2025


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Odds: Line |  O/U |  Money Line

9/19/2025 MLB Games
Time *ETMatchupPredictionActualResult
6:40 PM Athletics @ Pittsburgh Pirates  
Luis Severino vs Mitch Keller
O/U 8.5
+/- Lineups		Athletics
WIN 5.0-4.5
  by 0.5
Prediction
Athletics wins 4-3

 
6:40 PM Chicago Cubs @ Cincinnati Reds  
Shota Imanaga vs Nick Lodolo
O/U 8
+/- Lineups		Chicago Cubs
WIN 4.6-3.9
  by 0.6
Prediction
Cincinnati Reds wins 7-4

 
6:40 PM Atlanta Braves @ Detroit Tigers  
Bryce Elder vs Charlie Morton
O/U 9
+/- Lineups		Atlanta Braves
WIN 4.9-4.6
  by 0.3
Prediction
Atlanta Braves wins 10-1

 
7:05 PM New York Yankees @ Baltimore Orioles  
Will Warren vs Trevor Rogers
O/U 9
+/- Lineups		Baltimore Orioles
WIN 4.8-4.8
  by 0.1
Prediction
Baltimore Orioles wins 4-2

7:10 PM Washington Nationals @ New York Mets  
Andrew Alvarez vs Brandon Sproat
O/U 9
+/- Lineups		Washington Nationals
WIN 3.6-2.9
  by 0.7
Prediction
New York Mets wins 12-6

7:35 PM Boston Red Sox @ Tampa Bay Rays  
Garrett Crochet vs Drew Rasmussen
O/U 6.5
+/- Lineups		Boston Red Sox
WIN 4.1-3.5
  by 0.7
Prediction
Boston Red Sox wins 11-7

 
7:40 PM San Diego Padres @ Chicago White Sox  
Dylan Cease vs Davis Martin
O/U 8
+/- Lineups		San Diego Padres
WIN 4.4-3.6
  by 0.8
Prediction
Chicago White Sox wins 4-3

7:40 PM Toronto Blue Jays @ Kansas City Royals  
Max Scherzer vs Michael Lorenzen
O/U 9
+/- Lineups		Toronto Blue Jays
WIN 5.5-4.0
  by 1.5
Prediction
Kansas City Royals wins 20-1

 
8:05 PM Miami Marlins @ Texas Rangers  
Janson Junk vs Tyler Mahle
O/U 8
+/- Lineups		Miami Marlins
WIN 4.6-3.8
  by 0.8
Prediction
Miami Marlins wins 6-4

 
8:10 PM Seattle Mariners @ Houston Astros  
Bryan Woo vs Hunter Brown
O/U 7.5
+/- Lineups		Seattle Mariners
WIN 4.0-3.7
  by 0.3
Prediction
Seattle Mariners wins 4-0

8:10 PM Los Angeles Angels @ Colorado Rockies  
Mitch Farris vs Bradley Blalock
O/U 12
+/- Lineups		Los Angeles Angels
WIN 4.7-3.9
  by 0.8
Prediction
Colorado Rockies wins 7-6

8:10 PM Cleveland Guardians @ Minnesota Twins  
Parker Messick vs Pablo Lopez
O/U 7.5
+/- Lineups		Minnesota Twins
WIN 4.3-3.4
  by 0.9
Prediction
Cleveland Guardians wins 6-2

 
8:15 PM Milwaukee Brewers @ St. Louis Cardinals  
Jacob Misiorowski vs Sonny Gray
O/U 7.5
+/- Lineups		Milwaukee Brewers
WIN 4.8-3.7
  by 1.1
Prediction
St. Louis Cardinals wins 7-1

 
9:40 PM Philadelphia Phillies @ Arizona Diamondbacks  
Walker Buehler vs Ryne Nelson
O/U 9.5
+/- Lineups		Philadelphia Phillies
WIN 4.5-4.3
  by 0.1
Prediction
Philadelphia Phillies wins 8-2

10:10 PM San Francisco Giants @ Los Angeles Dodgers  
Robbie Ray vs Clayton Kershaw
O/U 9
+/- Lineups		Los Angeles Dodgers
WIN 4.5-3.7
  by 0.8
Prediction
Los Angeles Dodgers wins 6-3

Legend/Totals

Correct Picks 8 (53.3%)
Incorrect Picks 7 (46.7%)
Final Margin within 5 Runs 1 (6.7%)
Beat the Spread 7 (46.7%)
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