MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 6/21/2025


6/21/2025 MLB Games
Time *ETMatchupPredictionActualResult
12:10 PM Detroit Tigers @ Tampa Bay Rays  
Sawyer Gipson-Long vs Ryan Pepiot
-141 or 58.5%
+/- Lineups
Tampa Bay Rays
WIN 50.0% of sims
  by 0.2
Prediction
Tampa Bay Rays wins 8-3

1:05 PM Baltimore Orioles @ New York Yankees  
Zach Eflin vs Clarke Schmidt
-180 or 64.3%
+/- Lineups
New York Yankees
WIN 63.1% of sims
  by 1.0
Prediction
New York Yankees wins 9-0

2:10 PM Milwaukee Brewers @ Minnesota Twins  
Jose Quintana vs Simeon Woods Richardson
-135 or 57.4%
+/- Lineups
Minnesota Twins
WIN 55.9% of sims
  by 0.5
Prediction
Milwaukee Brewers wins 9-0

 
2:15 PM Cincinnati Reds @ St. Louis Cardinals  
Chase Petty vs Sonny Gray
-200 or 66.7%
+/- Lineups
Cincinnati Reds
WIN 51.3% of sims
  by 0.2
Prediction
St. Louis Cardinals wins 6-5

2:20 PM Seattle Mariners @ Chicago Cubs  
Emerson Hancock vs Cade Horton
-172 or 63.2%
+/- Lineups
Chicago Cubs
WIN 58.4% of sims
  by 0.5
Prediction
Chicago Cubs wins 10-7

3:07 PM Chicago White Sox @ Toronto Blue Jays  
Aaron Civale vs Jose Berrios
-215 or 68.3%
+/- Lineups
Toronto Blue Jays
WIN 68.2% of sims
  by 1.6
Prediction
Toronto Blue Jays wins 7-1

4:05 PM Texas Rangers @ Pittsburgh Pirates  
Kumar Rocker vs Mitch Keller
-110 or 52.4%
+/- Lineups
Pittsburgh Pirates
WIN 59.1% of sims
  by 0.7
Prediction
Texas Rangers wins 3-2

4:05 PM Boston Red Sox @ San Francisco Giants  
Brayan Bello vs Landen Roupp
-125 or 55.6%
+/- Lineups
San Francisco Giants
WIN 54.8% of sims
  by 0.6
Prediction
San Francisco Giants wins 3-2

 
4:10 PM Atlanta Braves @ Miami Marlins  
Grant Holmes vs Eury Perez
-134 or 57.3%
+/- Lineups
Atlanta Braves
WIN 59.4% of sims
  by 1.2
Prediction
Atlanta Braves wins 7-0

 
7:15 PM Kansas City Royals @ San Diego Padres  
Noah Cameron vs Dylan Cease
-154 or 60.6%
+/- Lineups
Kansas City Royals
WIN 53.7% of sims
  by 0.5
Prediction
San Diego Padres wins 5-1

7:15 PM New York Mets @ Philadelphia Phillies  
Griffin Canning vs Mick Abel
-102 or 50.5%
+/- Lineups
New York Mets
WIN 60.2% of sims
  by 1.3
Prediction
New York Mets wins 11-4

 
9:10 PM Arizona Diamondbacks @ Colorado Rockies  
Merrill Kelly vs Carson Palmquist
-166 or 62.4%
+/- Lineups
Arizona Diamondbacks
WIN 63.0% of sims
  by 2.0
Prediction
Arizona Diamondbacks wins 5-3

 
 
9:38 PM Houston Astros @ Los Angeles Angels  
Brandon Walter vs Jose Soriano
-130 or 56.5%
+/- Lineups
Houston Astros
WIN 61.6% of sims
  by 1.3
Prediction
Los Angeles Angels wins 9-1

10:05 PM Cleveland Guardians @ Athletics  
Luis Ortiz vs Mitch Spence
-114 or 53.3%
+/- Lineups
Athletics
WIN 58.3% of sims
  by 0.5
Prediction
Cleveland Guardians wins 4-2

10:10 PM Washington Nationals @ Los Angeles Dodgers  
Jake Irvin vs Dustin May
-275 or 73.3%
+/- Lineups
Los Angeles Dodgers
WIN 62.0% of sims
  by 1.2
Prediction
Washington Nationals wins 7-3

 

Legend/Totals

Correct Picks 7 (46.7%)
Incorrect Picks 8 (53.3%)
Final Margin within 5 Runs 2 (13.3%)
Beat the Spread 5 (33.3%)

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