MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 6/22/2025


6/22/2025 MLB Games
Time *ETMatchupPredictionActualResult
11:35 AM Baltimore Orioles @ New York Yankees  
Dean Kremer vs Will Warren
-220 or 68.8%
+/- Lineups
New York Yankees
WIN 66.4% of sims
  by 1.6
Prediction
New York Yankees wins 4-2

 
12:10 PM Detroit Tigers @ Tampa Bay Rays  
Casey Mize vs Zack Littell
-108 or 51.9%
+/- Lineups
Tampa Bay Rays
WIN 51.3% of sims
  by 0.1
Prediction
Detroit Tigers wins 9-3

 
1:35 PM Texas Rangers @ Pittsburgh Pirates  
Jack Leiter vs Bailey Falter
-118 or 54.1%
+/- Lineups
Pittsburgh Pirates
WIN 57.9% of sims
  by 0.7
Prediction
Pittsburgh Pirates wins 8-3

 
1:37 PM Chicago White Sox @ Toronto Blue Jays  
Adrian Houser vs Chris Bassitt
-203 or 67.0%
+/- Lineups
Toronto Blue Jays
WIN 56.7% of sims
  by 0.3
Prediction
Chicago White Sox wins 4-2

 
1:40 PM Atlanta Braves @ Miami Marlins  
Bryce Elder vs Sandy Alcantara
-133 or 57.1%
+/- Lineups
Atlanta Braves
WIN 54.0% of sims
  by 0.8
Prediction
Miami Marlins wins 5-3

 
2:10 PM Milwaukee Brewers @ Minnesota Twins  
Quinn Priester vs David Festa
-139 or 58.2%
+/- Lineups
Milwaukee Brewers
WIN 50.9% of sims
  by 0.4
Prediction
Milwaukee Brewers wins 9-8

 
 
2:15 PM Cincinnati Reds @ St. Louis Cardinals  
Andrew Abbott vs Miles Mikolas
-106 or 51.5%
+/- Lineups
Cincinnati Reds
WIN 65.3% of sims
  by 2.2
Prediction
Cincinnati Reds wins 4-1

 
 
2:20 PM Seattle Mariners @ Chicago Cubs  
Logan Gilbert vs Colin Rea
-108 or 51.9%
+/- Lineups
Seattle Mariners
WIN 65.7% of sims
  by 2.0
Prediction
Seattle Mariners wins 14-6

 
3:10 PM Arizona Diamondbacks @ Colorado Rockies  
Brandon Pfaadt vs Antonio Senzatela
-144 or 59.0%
+/- Lineups
Arizona Diamondbacks
WIN 62.0% of sims
  by 2.1
Prediction
Colorado Rockies wins 4-2

4:05 PM Cleveland Guardians @ Athletics  
Slade Cecconi vs JP Sears
-109 or 52.2%
+/- Lineups
Athletics
WIN 62.5% of sims
  by 1.0
Prediction
Cleveland Guardians wins 3-0

4:05 PM Boston Red Sox @ San Francisco Giants  
Lucas Giolito vs Robbie Ray
-164 or 62.1%
+/- Lineups
San Francisco Giants
WIN 54.9% of sims
  by 0.3
Prediction
San Francisco Giants wins 9-5

4:07 PM Houston Astros @ Los Angeles Angels  
Ryan Gusto vs Kyle Hendricks
-108 or 51.9%
+/- Lineups
Los Angeles Angels
WIN 53.9% of sims
  by 0.2
Prediction
Houston Astros wins 8-7

4:10 PM Washington Nationals @ Los Angeles Dodgers  
Michael Soroka vs Ben Casparius
-251 or 71.5%
+/- Lineups
Los Angeles Dodgers
WIN 68.6% of sims
  by 1.8
Prediction
Los Angeles Dodgers wins 13-7

4:10 PM Kansas City Royals @ San Diego Padres  
Seth Lugo vs Randy Vasquez
-122 or 55.0%
+/- Lineups
San Diego Padres
WIN 56.3% of sims
  by 0.3
Prediction
San Diego Padres wins 3-2

 
 
7:10 PM New York Mets @ Philadelphia Phillies  
David Peterson vs Jesus Luzardo
-119 or 54.3%
+/- Lineups
New York Mets
WIN 57.8% of sims
  by 1.3
Prediction
Philadelphia Phillies wins 7-1

Legend/Totals

Correct Picks 8 (53.3%)
Incorrect Picks 7 (46.7%)
Final Margin within 5 Runs 4 (26.7%)
Beat the Spread 8 (53.3%)

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