MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 7/22/2025


7/22/2025 MLB Games
Time *ETMatchupPredictionActualResult
6:40 PM Baltimore Orioles @ Cleveland Guardians  
Brandon Young vs Joey Cantillo
-161 or 61.7%
+/- Lineups
Cleveland Guardians
WIN 71.5% of sims
  by 1.8
Prediction
Cleveland Guardians wins 6-3

 
6:40 PM Detroit Tigers @ Pittsburgh Pirates  
Casey Mize vs Mitch Keller
-114 or 53.3%
+/- Lineups
Detroit Tigers
WIN 52.6% of sims
  by 0.5
Prediction
Pittsburgh Pirates wins 8-5

 
6:40 PM San Diego Padres @ Miami Marlins  
Stephen Kolek vs Edward Cabrera
-131 or 56.7%
+/- Lineups
Miami Marlins
WIN 58.1% of sims
  by 0.5
Prediction
Miami Marlins wins 4-3

 
 
6:45 PM Cincinnati Reds @ Washington Nationals  
Chase Burns vs Brad Lord
-120 or 54.5%
+/- Lineups
Washington Nationals
WIN 56.4% of sims
  by 0.3
Prediction
Washington Nationals wins 6-1

 
6:45 PM Boston Red Sox @ Philadelphia Phillies  
Richard Fitts vs Cristopher Sanchez
-188 or 65.3%
+/- Lineups
Boston Red Sox
WIN 51.1% of sims
  by 0.4
Prediction
Philadelphia Phillies wins 4-1

7:05 PM Chicago White Sox @ Tampa Bay Rays  
Davis Martin vs Drew Rasmussen
-239 or 70.5%
+/- Lineups
Tampa Bay Rays
WIN 60.9% of sims
  by 0.9
Prediction
Tampa Bay Rays wins 4-3

 
7:07 PM New York Yankees @ Toronto Blue Jays  
Cam Schlittler vs Max Scherzer
-118 or 54.1%
+/- Lineups
New York Yankees
WIN 61.1% of sims
  by 1.5
Prediction
New York Yankees wins 5-4

 
 
7:10 PM Los Angeles Angels @ New York Mets  
Kyle Hendricks vs Frankie Montas
-166 or 62.4%
+/- Lineups
New York Mets
WIN 59.2% of sims
  by 0.8
Prediction
New York Mets wins 3-2

 
7:15 PM San Francisco Giants @ Atlanta Braves  
Landen Roupp vs Davis Daniel
-120 or 54.5%
+/- Lineups
Atlanta Braves
WIN 59.7% of sims
  by 0.6
Prediction
San Francisco Giants wins 9-0

8:05 PM Kansas City Royals @ Chicago Cubs  
Rich Hill vs Matthew Boyd
-263 or 72.5%
+/- Lineups
Chicago Cubs
WIN 68.2% of sims
  by 1.5
Prediction
Chicago Cubs wins 6-0

8:05 PM Athletics @ Texas Rangers  
J.T. Ginn vs Jacob deGrom
-225 or 69.2%
+/- Lineups
Texas Rangers
WIN 52.0% of sims
  by 0.1
Prediction
Texas Rangers wins 6-2

8:40 PM St. Louis Cardinals @ Colorado Rockies  
Erick Fedde vs Bradley Blalock
-140 or 58.3%
+/- Lineups
Colorado Rockies
WIN 51.0% of sims
  by 0.3
Prediction
Colorado Rockies wins 8-4

 
9:40 PM Houston Astros @ Arizona Diamondbacks  
Framber Valdez vs Eduardo Rodriguez
-105 or 51.2%
+/- Lineups
Houston Astros
WIN 56.9% of sims
  by 0.9
Prediction
Houston Astros wins 3-1

 
9:40 PM Milwaukee Brewers @ Seattle Mariners  
Jacob Misiorowski vs Logan Gilbert
-132 or 56.9%
+/- Lineups
Seattle Mariners
WIN 59.6% of sims
  by 0.7
Prediction
Seattle Mariners wins 1-0

 
 
10:10 PM Minnesota Twins @ Los Angeles Dodgers  
Simeon Woods Richardson vs Yoshinobu Yamamoto
-199 or 66.6%
+/- Lineups
Los Angeles Dodgers
WIN 69.1% of sims
  by 1.8
Prediction
Minnesota Twins wins 10-7

Legend/Totals

Correct Picks 10 (66.7%)
Incorrect Picks 5 (33.3%)
Final Margin within 5 Runs 5 (33.3%)
Beat the Spread 8 (53.3%)

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