MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 8/22/2025


8/22/2025 MLB Games
Time *ETMatchupPredictionActualResult
6:40 PM Colorado Rockies @ Pittsburgh Pirates  
Antonio Senzatela vs Braxton Ashcraft
-232 or 69.9%
+/- Lineups
Pittsburgh Pirates
WIN 62.9% of sims
  by 1.0
Prediction
Pittsburgh Pirates wins 9-0

6:45 PM Washington Nationals @ Philadelphia Phillies  
Cade Cavalli vs Taijuan Walker
-194 or 66.0%
+/- Lineups
Philadelphia Phillies
WIN 56.4% of sims
  by 0.5
Prediction
Washington Nationals wins 5-4

 
7:05 PM Houston Astros @ Baltimore Orioles  
Lance McCullers Jr. vs Cade Povich
-104 or 51.0%
+/- Lineups
Houston Astros
WIN 53.8% of sims
  by 0.7
Prediction
Houston Astros wins 10-7

 
7:05 PM Boston Red Sox @ New York Yankees  
Brayan Bello vs Max Fried
-199 or 66.6%
+/- Lineups
New York Yankees
WIN 64.3% of sims
  by 1.5
Prediction
Boston Red Sox wins 1-0

 
7:10 PM Kansas City Royals @ Detroit Tigers  
Ryan Bergert vs Casey Mize
-162 or 61.8%
+/- Lineups
Detroit Tigers
WIN 51.0% of sims
  by 0.2
Prediction
Detroit Tigers wins 7-5

7:10 PM Toronto Blue Jays @ Miami Marlins  
Shane Bieber vs Ryan Gusto
-136 or 57.6%
+/- Lineups
Toronto Blue Jays
WIN 52.3% of sims
  by 0.6
Prediction
Toronto Blue Jays wins 5-2

7:15 PM New York Mets @ Atlanta Braves  
Nolan McLean vs Joey Wentz
-116 or 53.7%
+/- Lineups
Atlanta Braves
WIN 66.1% of sims
  by 1.2
Prediction
New York Mets wins 12-7

7:35 PM St. Louis Cardinals @ Tampa Bay Rays  
Miles Mikolas vs Adrian Houser
-139 or 58.2%
+/- Lineups
St. Louis Cardinals
WIN 58.1% of sims
  by 1.3
Prediction
Tampa Bay Rays wins 10-6

7:40 PM Minnesota Twins @ Chicago White Sox  
Zebby Matthews vs Aaron Civale
-110 or 52.4%
+/- Lineups
Chicago White Sox
WIN 53.5% of sims
  by 0.1
Prediction
Minnesota Twins wins 9-7

8:05 PM Cleveland Guardians @ Texas Rangers  
Slade Cecconi vs Nathan Eovaldi
-164 or 62.1%
+/- Lineups
Texas Rangers
WIN 58.0% of sims
  by 0.7
Prediction
Texas Rangers wins 4-3

 
8:10 PM San Francisco Giants @ Milwaukee Brewers  
Carson Whisenhunt vs Jose Quintana
-184 or 64.8%
+/- Lineups
Milwaukee Brewers
WIN 68.0% of sims
  by 1.5
Prediction
Milwaukee Brewers wins 5-4

 
 
9:38 PM Chicago Cubs @ Los Angeles Angels  
Javier Assad vs Tyler Anderson
-109 or 52.2%
+/- Lineups
Los Angeles Angels
WIN 52.0% of sims
  by 0.1
Prediction
Chicago Cubs wins 3-2

9:40 PM Cincinnati Reds @ Arizona Diamondbacks  
Zack Littell vs Ryne Nelson
-136 or 57.6%
+/- Lineups
Arizona Diamondbacks
WIN 54.3% of sims
  by 0.1
Prediction
Arizona Diamondbacks wins 6-5

 
9:40 PM Los Angeles Dodgers @ San Diego Padres  
Blake Snell vs Yu Darvish
-104 or 51.0%
+/- Lineups
San Diego Padres
WIN 54.4% of sims
  by 0.0
Prediction
San Diego Padres wins 2-1

 
 
10:10 PM Athletics @ Seattle Mariners  
Luis Morales vs Bryan Woo
-221 or 68.8%
+/- Lineups
Seattle Mariners
WIN 60.1% of sims
  by 0.9
Prediction
Seattle Mariners wins 3-2

 

Legend/Totals

Correct Picks 8 (53.3%)
Incorrect Picks 7 (46.7%)
Final Margin within 5 Runs 5 (33.3%)
Beat the Spread 5 (33.3%)

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