MLB Predictions & Baseball Game Simulator - MyGameSim.com

MLB Predictions for 9/20/2025


9/20/2025 MLB Games
Time *ETMatchupPredictionActualResult
1:10 PM Atlanta Braves @ Detroit Tigers  
Joey Wentz vs Keider Montero
-120 or 54.5%
+/- Lineups
Detroit Tigers
WIN 55.5% of sims
  by 0.2
Prediction
Atlanta Braves wins 6-5

2:10 PM Cleveland Guardians @ Minnesota Twins  
Slade Cecconi vs Joe Ryan
-108 or 51.9%
+/- Lineups
Minnesota Twins
WIN 59.3% of sims
  by 0.6
Prediction
Cleveland Guardians wins 6-0

4:10 PM Washington Nationals @ New York Mets  
Cade Cavalli vs Nolan McLean
-301 or 75.1%
+/- Lineups
New York Mets
WIN 73.1% of sims
  by 2.3
Prediction
Washington Nationals wins 5-3

 
6:40 PM Athletics @ Pittsburgh Pirates  
Luis Morales vs Bubba Chandler
-107 or 51.7%
+/- Lineups
Athletics
WIN 59.9% of sims
  by 1.2
Prediction
Pittsburgh Pirates wins 2-0

6:40 PM Chicago Cubs @ Cincinnati Reds  
Javier Assad vs Zack Littell
-114 or 53.3%
+/- Lineups
Cincinnati Reds
WIN 55.6% of sims
  by 0.2
Prediction
Cincinnati Reds wins 6-3

 
7:05 PM Boston Red Sox @ Tampa Bay Rays  
Kyle Harrison vs Adrian Houser
-113 or 53.1%
+/- Lineups
Boston Red Sox
WIN 60.1% of sims
  by 1.3
Prediction
Boston Red Sox wins 6-3

 
7:05 PM Miami Marlins @ Texas Rangers  
Adam Mazur vs Jack Leiter
-146 or 59.3%
+/- Lineups
Texas Rangers
WIN 53.7% of sims
  by 0.1
Prediction
Miami Marlins wins 4-3

 
 
7:05 PM New York Yankees @ Baltimore Orioles  
Carlos Rodon vs Tomoyuki Sugano
-164 or 62.1%
+/- Lineups
New York Yankees
WIN 69.7% of sims
  by 2.2
Prediction
New York Yankees wins 6-1

 
7:10 PM Seattle Mariners @ Houston Astros  
George Kirby vs Framber Valdez
-109 or 52.2%
+/- Lineups
Houston Astros
WIN 54.9% of sims
  by 0.0
Prediction
Seattle Mariners wins 6-4

7:10 PM San Diego Padres @ Chicago White Sox  
Yu Darvish vs Yoendrys Gomez
-153 or 60.5%
+/- Lineups
San Diego Padres
WIN 53.6% of sims
  by 0.7
Prediction
San Diego Padres wins 7-3

7:10 PM Toronto Blue Jays @ Kansas City Royals  
Shane Bieber vs Noah Cameron
-111 or 52.6%
+/- Lineups
Toronto Blue Jays
WIN 52.1% of sims
  by 0.3
Prediction
Kansas City Royals wins 2-1

 
7:10 PM Cleveland Guardians @ Minnesota Twins  
Logan Allen vs Bailey Ober
-108 or 51.9%
+/- Lineups
Cleveland Guardians
WIN 50.3% of sims
  by 0.4
Prediction
Cleveland Guardians wins 8-0

 
7:15 PM Milwaukee Brewers @ St. Louis Cardinals  
Chad Patrick vs Miles Mikolas
-121 or 54.8%
+/- Lineups
Milwaukee Brewers
WIN 55.3% of sims
  by 0.9
Prediction
Milwaukee Brewers wins 3-2

 
 
8:10 PM Philadelphia Phillies @ Arizona Diamondbacks  
Aaron Nola vs Zac Gallen
-112 or 52.8%
+/- Lineups
Arizona Diamondbacks
WIN 57.4% of sims
  by 0.6
Prediction
Arizona Diamondbacks wins 4-3

 
 
8:10 PM Los Angeles Angels @ Colorado Rockies  
Kyle Hendricks vs German Marquez
-107 or 51.7%
+/- Lineups
Los Angeles Angels
WIN 55.7% of sims
  by 0.9
Prediction
Los Angeles Angels wins 3-0

 
9:10 PM San Francisco Giants @ Los Angeles Dodgers  
Kai-Wei Teng vs Tyler Glasnow
-232 or 69.9%
+/- Lineups
Los Angeles Dodgers
WIN 66.5% of sims
  by 1.8
Prediction
Los Angeles Dodgers wins 7-5

 

Legend/Totals

Correct Picks 10 (62.5%)
Incorrect Picks 6 (37.5%)
Final Margin within 5 Runs 4 (25.0%)
Beat the Spread 10 (62.5%)

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