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Predictions refresh daily and may update during the day when key injuries or depth chart changes occur.

MLB Predictions for 6/5/2025

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Odds: Line | O/U | Money Line

6/5/2025 MLB Games
Time *ET	Matchup	Prediction	Actual	Result
12:15 PM	Arizona Diamondbacks @ Atlanta Braves Brandon Pfaadt vs Grant Holmes by 1.5 +/- Lineups Corbin Carroll RF Ketel Marte 2B Geraldo Perdomo SS Josh Naylor DH Eugenio Suarez 3B Lourdes Gurriel LF Pavin Smith 1B Alek Thomas CF Jose Herrera C Brandon Pfaadt P Ronald Acuna RF Drake Baldwin C Austin Riley 3B Matt Olson 1B Marcell Ozuna DH Ozzie Albies 2B Alex Verdugo LF Nick Allen SS Michael Harris CF Grant Holmes P	Atlanta Braves WIN 4.8-4.6 by 0.2 Prediction	Arizona Diamondbacks wins 11-10
1:45 PM	Kansas City Royals @ St. Louis Cardinals Noah Cameron vs Miles Mikolas by 1.5 +/- Lineups Jonathan India DH Bobby Witt SS Maikel Garcia 3B Vinnie Pasquantino 1B Salvador Perez C Jac Caglianone RF Drew Waters LF Michael Massey 2B Kyle Isbel CF Noah Cameron P Lars Nootbaar CF Masyn Winn SS Brendan Donovan 2B Willson Contreras 1B Ivan Herrera DH Nolan Arenado 3B Alec Burleson LF Ryan Vilade RF Pedro Pages C Miles Mikolas P	Kansas City Royals WIN 3.6-3.4 by 0.2 Prediction	St. Louis Cardinals wins 6-5
2:10 PM	Detroit Tigers @ Chicago White Sox Casey Mize vs Sean Burke by 1.5 +/- Lineups Parker Meadows CF Gleyber Torres 2B Kerry Carpenter DH Spencer Torkelson 1B Wenceel Perez RF Zach McKinstry LF Javier Baez 3B Trey Sweeney SS Jake Rogers C Casey Mize P Mike Tauchman RF Chase Meidroth 2B Edgar Quero C Andrew Benintendi DH Joshua Palacios LF Tim Elko 1B Josh Rojas 3B Michael Taylor CF Vinny Capra SS Sean Burke P	Detroit Tigers WIN 3.8-3.6 by 0.2 Prediction	Chicago White Sox wins 3-2
3:07 PM	Philadelphia Phillies @ Toronto Blue Jays Jesus Luzardo vs Chris Bassitt by 1.5 +/- Lineups Bryson Stott 2B Trea Turner SS Bryce Harper 1B Kyle Schwarber DH Alec Bohm 3B Nick Castellanos RF Max Kepler LF Brandon Marsh CF Rafael Marchan C Jesus Luzardo P Bo Bichette SS Vladimir Guerrero 1B George Springer RF Alejandro Kirk DH Ernie Clement 3B Davis Schneider 2B Myles Straw CF Jonatan Clase LF Tyler Heineman C Chris Bassitt P	Philadelphia Phillies WIN 4.5-4.4 by 0.2 Prediction	Toronto Blue Jays wins 9-1
3:35 PM	Minnesota Twins @ Athletics David Festa vs Mitch Spence by 1.5 +/- Lineups Byron Buxton CF Trevor Larnach DH Ryan Jeffers C Matt Wallner RF Willi Castro 3B Ty France 1B Kody Clemens 2B Brooks Lee SS Harrison Bader LF David Festa P Lawrence Butler RF Jacob Wilson SS Brent Rooker LF Tyler Soderstrom 1B Shea Langeliers DH Max Muncy 3B Willie MacIver C Max Schuemann 2B Denzel Clarke CF Mitch Spence P	Minnesota Twins WIN 4.7-3.9 by 0.7 Prediction	Athletics wins 14-3
3:40 PM	Baltimore Orioles @ Seattle Mariners Zach Eflin vs Bryan Woo by 1.5 +/- Lineups Jackson Holliday 2B Adley Rutschman DH Gunnar Henderson SS Ryan O'Hearn 1B Dylan Carlson LF Heston Kjerstad RF Emmanuel Rivera 3B Jorge Mateo CF Maverick Handley C Zach Eflin P J.P. Crawford SS Jorge Polanco DH Julio Rodriguez CF Cal Raleigh C Randy Arozarena LF Rowdy Tellez 1B Leody Taveras RF Miles Mastrobuoni 3B Cole Young 2B Bryan Woo P	Seattle Mariners WIN 4.2-3.1 by 1.0 Prediction	Baltimore Orioles wins 4-3
3:45 PM	San Diego Padres @ San Francisco Giants Dylan Cease vs Robbie Ray by 1.5 +/- Lineups Fernando Tatis RF Luis Arraez 1B Manny Machado 3B Jackson Merrill CF Gavin Sheets DH Jose Iglesias SS Jake Cronenworth 2B Brandon Lockridge LF Martin Maldonado C Dylan Cease P Daniel Johnson RF Heliot Ramos DH Jung Hoo Lee CF Matt Chapman 3B Willy Adames SS Dominic Smith 1B Jerar Encarnacion LF Tyler Fitzgerald 2B Andrew Knizner C Robbie Ray P	San Francisco Giants WIN 4.4-4.2 by 0.3 Prediction	San Francisco Giants wins 3-2
4:10 PM	New York Mets @ Los Angeles Dodgers David Peterson vs Landon Knack by 1.5 +/- Lineups Brandon Nimmo LF Starling Marte DH Juan Soto RF Pete Alonso 1B Jeff McNeil 2B Tyrone Taylor CF Brett Baty 3B Francisco Alvarez C Luisangel Acuna SS David Peterson P Shohei Ohtani DH Mookie Betts SS Will Smith C Teoscar Hernandez RF Andy Pages CF Tommy Edman 2B Enrique Hernandez 1B Michael Conforto LF Miguel Rojas 3B Landon Knack P	Los Angeles Dodgers WIN 5.3-4.6 by 0.7 Prediction	Los Angeles Dodgers wins 6-5
6:40 PM	Houston Astros @ Pittsburgh Pirates Framber Valdez vs Mitch Keller by 1.5 +/- Lineups Jeremy Pena SS Isaac Paredes 3B Jose Altuve DH Christian Walker 1B Yainer Diaz C Jake Meyers CF Cam Smith RF Jacob Melton LF Mauricio Dubon 2B Framber Valdez P Oneil Cruz CF Andrew McCutchen DH Bryan Reynolds RF Nick Gonzales 2B Ke'Bryan Hayes 3B Tommy Pham LF Henry Davis C Jared Triolo 1B Isiah Kiner-Falefa SS Mitch Keller P	Houston Astros WIN 4.3-2.8 by 1.5 Prediction	Houston Astros wins 8-2
6:45 PM	Chicago Cubs @ Washington Nationals Colin Rea vs Jake Irvin by 1.5 +/- Lineups Ian Happ LF Kyle Tucker RF Seiya Suzuki DH Pete Crow-Armstrong CF Dansby Swanson SS Michael Busch 1B Nico Hoerner 2B Matt Shaw 3B Reese McGuire C Colin Rea P CJ Abrams SS Amed Rosario 3B James Wood LF Nathaniel Lowe 1B Keibert Ruiz C Josh Bell DH Alex Call RF Luis Garcia 2B Robert Hassell CF Jake Irvin P	Washington Nationals WIN 4.7-4.2 by 0.5 Prediction	Chicago Cubs wins 7-1
7:05 PM	Cleveland Guardians @ New York Yankees Slade Cecconi vs Max Fried by 1.5 +/- Lineups Steven Kwan LF Angel Martinez CF Jose Ramirez 3B David Fry DH Carlos Santana 1B Gabriel Arias SS Bo Naylor C Nolan Jones RF Will Wilson 2B Slade Cecconi P Trent Grisham CF Ben Rice 1B Aaron Judge DH Cody Bellinger RF Jazz Chisholm 3B Anthony Volpe SS Jasson Dominguez LF Austin Wells C Oswald Peraza 2B Max Fried P	New York Yankees WIN 6.1-3.2 by 2.9 Prediction	New York Yankees wins 4-0
7:35 PM	Texas Rangers @ Tampa Bay Rays Jack Leiter vs Ryan Pepiot by 1.5 +/- Lineups Josh Smith 1B Wyatt Langford CF Corey Seager SS Josh Jung 3B Alejandro Osuna LF Marcus Semien 2B Adolis Garcia RF Jake Burger DH Jonah Heim C Jack Leiter P Josh Lowe RF Brandon Lowe 2B Yandy Diaz DH Jonathan Aranda 1B Junior Caminero 3B Kameron Misner CF Christopher Morel LF Taylor Walls SS Danny Jansen C Ryan Pepiot P	Texas Rangers WIN 3.9-3.8 by 0.1 Prediction	Tampa Bay Rays wins 4-3
7:45 PM	Kansas City Royals @ St. Louis Cardinals Cole Ragans vs Matthew Liberatore by 1.5 +/- Lineups Jonathan India 2B Bobby Witt SS Maikel Garcia CF Vinnie Pasquantino DH Salvador Perez 1B Jac Caglianone RF Mark Canha LF Nick Loftin 3B Freddy Fermin C Cole Ragans P Lars Nootbaar LF Masyn Winn SS Brendan Donovan 2B Willson Contreras 1B Ivan Herrera DH Nolan Arenado 3B Yohel Pozo C Ryan Vilade RF Victor Scott CF Matthew Liberatore P	St. Louis Cardinals WIN 4.0-2.8 by 1.2 Prediction	Kansas City Royals wins 7-5

Legend/Totals

Correct Picks	4 (30.8%)
Incorrect Picks	9 (69.2%)
Final Margin within 5 Runs	2 (15.4%)
Beat the Spread	10 (76.9%)

MLB Predictions for 6/5/2025

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