NFL Predictions & Game Simulator - MyGameSim.com

NFL Predictions for Week 4

Looking like a big day for Puka Nacua (Rams). In this week's simulations, he averaged 125.6 receiving yards per game.
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Week 4 NFL Games
Date/TimeMatchupPredictionActualResult
9/7/2025 4:05 PM  San Francisco 49ers @ Seattle Seahawks 
by 1.5
Seattle Seahawks
WIN 22.4-20.1
won 54.87% of sims, average margin of 2.3
Prediction
Projected Stats
San Francisco 49ers wins 17-13

 
9/14/2025 1 PM  San Francisco 49ers @ New Orleans Saints 
by 3
San Francisco 49ers
WIN 19.5-18.0
won 54.33% of sims, average margin of 1.5
Prediction
Projected Stats
San Francisco 49ers wins 26-21

 
9/21/2025 4:25 PM  Arizona Cardinals @ San Francisco 49ers 
by 2.5
Arizona Cardinals
WIN 15.0-12.0
won 59.53% of sims, average margin of 3.1
Prediction
Projected Stats
San Francisco 49ers wins 16-15

 
 
9/28/2025 4:05 PM  Jacksonville Jaguars @ San Francisco 49ers 
by 3.5
San Francisco 49ers
WIN 18.2-15.4
won 61.43% of sims, average margin of 2.8
Prediction | Simulate
Projected Stats
 

 

Legend/Totals

Correct Picks 1 (33.3%)
Incorrect Picks 2 (66.7%)
Final Margin within 7 Pts 3 (100.0%)
Beat the Spread 1 (33.3%)

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